Protein–protein interaction networks studies and importance of 3D structure knowledge
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Summary
3D interactome networks, which offer detailed information at the atomic level, are focused on, highlighting their contribution to the studies in genotype–phenotype relationships and in the optimization of targeted studies to design novel chemical compounds for medical treatments.
- Type
- review
- Published
- 2013-12-01
- Cited by
- 23
- References
- 126
- OpenAlex
- https://openalex.org/W2075378764
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10194508
Keywords
Interactome, Computational biology, Protein–protein interaction, Protein Interaction Networks, Computer science
References
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Cited by
- Predicting Protein-Protein Interactions from Primary Protein Sequences Using a Novel Multi-Scale Local Feature Representation Scheme and the Random Forest
- Anatomy of protein disorder, flexibility and disease-related mutations
- Bridging topological and functional information in protein interaction networks by short loops profiling
- How do oncoprotein mutations rewire protein-protein interaction networks? Perspectives and techniques
- Modulators of protein-protein interactions.
- Hydrolytic inhibition of α-chymotrypsin by 2,8,14,20-tetrakis(D-leucyl-D-valinamido)resorc[4]arenecarboxylic acid: a spectroscopic NMR and computational combined approach.
- PinSnps: structural and functional analysis of SNPs in the context of protein interaction networks
- Function and Flexibility: Friend or Foe?
- Hidden partners: Using cross-docking calculations to predict binding sites for proteins with multiple interactions
- Modulating Protein–Protein Interactions with Visible‐Light‐Responsive Peptide Backbone Photoswitches
- Developing a computational approach to investigate the impacts of disease-causing mutations on protein function
- Network Medicine in the Age of Biomedical Big Data
- Do available protein 3D structures reflect human genetic and functional diversity?
- Omic approaches to decipher the molecular mechanisms of fibrosis, and design new anti-fibrotic strategies.
- Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks
- mPPI: a database extension to visualize structural interactome in a one-to-many manner
- Disease Evolution-based Specificity Target Discovery (DESTD) by analyzing Jiawei-Maxing-shigan Decoctions against COVID-19
- PINDER: The protein interaction dataset and evaluation resource
- Characterisation of guided entry of tail-anchored proteins in Magnaporthe oryzae
- New insights into translational research in Alzheimer's disease guided by artificial intelligence, computational and systems biology
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