Preparation of a psammaplysene-based library.

Summary

A 28-member focused library, based on the pseudosymmetric template of the marine alkaloids psammaplysenes, was prepared from combinations of components that were, in turn, derived from 4-iodophenol.

Keywords

Chemistry, Combinatorial chemistry, Stereochemistry, Nanotechnology, Computational biology

References

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Recent Progress in the Use of N-Halo Compounds in Organic SynthesisHojat Veisi, Ramin Ghorbani‐Vaghei, Mohammad Ali Zolfigol — 2011
FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseasesJelena Mojsilovic-Petrovic, Natalia B. Nedelsky, Marco Boccitto — 2009
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Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1Emily Berry, Jennifer Hardt, Jon Clardy — 2008
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