Boswellic acid suppresses cyclophosphamide induced chromosomal damage in mice
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Summary
Boswellic acid itself doesn’t have any genotoxic effect and suppresses genotoxicity induced by cyclophosphamide and inhibited chromosomal aberrations in mice, whereas Boswellic Acid alone did not either induce formation of micronuclei or chromosomal aberration in mice.
- Type
- article
- Published
- 2011-07-27
- Cited by
- 4
- References
- 30
- OpenAlex
- https://openalex.org/W2074973372
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1227004
Keywords
Micronucleus test, Genotoxicity, Micronucleus, Cyclophosphamide, Chemistry
References
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- Mutagenicity Testing: a Practical Approach
- Citrus extract modulates genotoxicity induced by cyclophosphamide in mice bone marrow cells
- Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis.
- Internal hazards: baseline DNA damage by endogenous products of normal metabolism.
- An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen. 2. Studies with chlorambucil and mitomycin C.
- Recommended protocols based on a survey of current practice in genotoxicity testing laboratories, IV. Chromosome aberration and sister-chromatid exchange in Chinese hamster ovary, V79 Chinese hamster lung and human lymphocyte cultures.
- The Risk–Benefit Profile of Commonly Used Herbal Therapies
- Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid.
- Assessment of the potential genotoxic risk of Phyllantus orbicularis HBK aqueous extract using in vitro and in vivo assays.
- Lack of clastogenic/genotoxic effects of Baccharis dracunculifolia extract on Swiss mouse peripheral blood cells.
- Antiinflammatory and Antiatherogenic Effects of the NF-&kgr;B Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE−/− Mice
- The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
- Antigenotoxic effects of Mandevilla velutina (Gentianales, Apocynaceae) crude extract on cyclophosphamide-induced micronuclei in Swiss mice and urethane-induced somatic mutation and recombination in Drosophila melanogaster
- The risk-benefit profile of commonly used herbal therapies.
- An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen. 1. Studies with cyclophosphamide.
- Cardiovascular effects of ephedra alkaloids: a comprehensive review.
- Use of cyclophosphamide as a positive control in dominant lethal and micronucleus assays.
- Protection by boswellic acids against galactosamine/endotoxin-induced hepatitis in mice.
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