Vitamins B12, B6 and folate as determinants of homocysteine concentration in the healthy population
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Summary
It may be necessary to redefine an adequate blood folate level and probably reformulate dietary allowances for this B-vitamin due to the important role of folate status as a determinant of homocysteine concentration.
- Type
- review
- Published
- 1998-03-24
- Cited by
- 80
- References
- 13
- OpenAlex
- https://openalex.org/W2074354890
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19681739
Keywords
Homocysteine, Vitamin B12, Medicine, B vitamins, Population
References
- Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
- Controlled dietary folate affects folate status in nonpregnant women.
- Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status.
- Vitamin requirements for the treatment of hyperhomocysteinemia in humans.
- The use of homocysteine and other metabolites in the specific diagnosis of vitamin B-12 deficiency.
- Results of B-vitamin supplementation study used in a prediction model to define a reference range for plasma homocysteine.
- Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
- Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease.
- Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor.
- Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
- Kinetics of total plasma homocysteine in subjects with hyperhomocysteinemia due to folate or cobalamin deficiency.
- Folate deficiency: morphological and functional consequences.
- Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations.
Cited by
- Increased plasma homocysteine levels in shift working bus drivers
- Induction and Prevention of Cleft Lip, Alveolus and Palate and Neural Tube Defects with Special Consideration of B Vitamins and the Methylation Cycle
- Evaluation of a modified paleolithic dietary intervention for the treatment of relapsing-remitting multiple sclerosis
- Homocisteinemia basal y post sobrecargade metionina:Experiencia en una Unidad de Prevencióny Seguimiento de Riesgo Cardiovascular
- Traditional and alternative nutrition - levels of homocysteine and lipid parameters in adults
- Thrombophilie bei Patienten mit venösen Ulzera
- Assessment of vitamin B-12, folate, and vitamin B-6 status and relation to sulfur amino acid metabolism in neonates.
- Metabolism of Mycotoxins, Intracellular Functions of Vitamin B12, and Neurological Manifestations in Patients with Chronic Toxigenic Mold Exposures. A Review
- Relevance of post‐methionine homocysteine and lipoprotein (a) in evaluating the cardiovascular risk in young CAD patients
- Determinants of homocysteine levels in Ivorian rural population.
- Endothelial Function in Healthy Younger and Older Hyperhomocysteinemic Subjects
- The polyphenol-rich extract from grape seeds suppresses toxicity of homocysteine and its thiolactone on the fibrinolytic system.
- The S-adenosyl homocysteine hydrolase inhibitor 3-deaza-adenosine prevents oxidative damage and cognitive impairment following folate and vitamin E deprivation in a murine model of age-related, oxidative stress-induced neurodegeneration
- Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats.
- [Socio-demographic, lifestyle, gynecological, and obstetric predictors of serum or plasma concentrations of homocysteine, folic acid, and vitamins B12 and B6 among low-income women in São Paulo, Brazil].
- Homocysteine as a determinant of left ventricular ejection fraction in patients with diabetes
- Effect of increased vegetable and fruit consumption on plasma folate and homocysteine concentrations.
- The effect of folic acid, vitamin B6 and vitamin B12 on the homocysteine levels in rabbits fed by methionine-enriched diets.
- Revisiting the Evidence for Neuropathy Caused by Pyridoxine Deficiency and Excess
- Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation
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