FOXP3+ regulatory T cells in the human immune system

Keywords

FOXP3, Biology, T cell, Phenotype, Immune system

References

• Human regulatory T cells and their role in autoimmune diseaseIldefonso Damas Hurtado — 2006
• CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-β–dependent mannerStuart R. Cohn — 2008
• Comment on “Cutting Edge: Human CD4−CD8− Thymocytes Express FOXP3 in the Absence of a TCR”Alessandra Battaglia, Amelia Evoli, Giovanni Scambia — 2008
• The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell — 2001
• X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfyRobert S. Wildin, Fred Ramsdell, Jane Peake — 2001
• Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism1David Gondek, Li‐Fan Lu, Sergio A. Quezada — 2005
• Cell interactions in the induction of tolerance: the role of thymic lymphocytes.Richard K. Gershon, Kazunari Kondo — 1970
• Ontogeny of human T cells.Daniel P. Stites, Charles S. Pavia — 1979
• CD4+CD25high Regulatory Cells in Human Peripheral Blood1Clare Baecher‐Allan, Julia A. Brown, Gordon J. Freeman — 2001
• Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseMary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild — 2001
• Large scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cellsPetra Hoffmann, Ruediger Eder, LA Kunz-Schughart — 2004
• Analysis of FOXP3 Reveals Multiple Domains Required for Its Function as a Transcriptional Repressor1Jared E. Lopes, Troy R. Torgerson, Lisa Schubert — 2006
• Cutting Edge: Responder T Cells Regulate Human DR+ Effector Regulatory T Cell Activity via Granzyme B1Charles Ashley, Clare Baecher‐Allan — 2009
• Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25− lymphocytesFabienne Venet, Alexandre Pachot, Anne‐Lise Debard — 2004
• OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset [published erratum appears in J Exp Med 1991 Apr 1;173(4):1037]Fiona Powrie, Don Mason — 1990
• Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells.Estelle Bettelli, Maryam Dastrange, Mohamed Oukka — 2005
• Antigen‐specific T cell suppression by human CD4+CD25+ regulatory T cellsLeonie S. Taams, Milica Vukmanovic‐Stejic, J. Maynard Smith — 2002
• Human thymic stromal lymphopoietin promotes dendritic cell–mediated CD4+ T cell homeostatic expansionNorihiko Watanabe, Shino Hanabuchi, Vassili Soumelis — 2004
• Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humansMaria Grazia Roncarolo, Silvia Gregori, Manuela Battaglia — 2006
• IL-2 Family of Cytokines in T Regulatory Cell Development and HomeostasisThomas R. Malek, Aixin Yu, Linjian Zhu — 2008

Cited by

• Understanding Recurrent Disease: A Dynamical Systems ApproachWenjing Zhang — 2014
• The microRNA regulatory network in normal- and HTLV-1-transformed T cells.Donna M. D’Agostino, Paola Zanovello, Toshiki Watanabe — 2012
• The biological and clinical significance of the maternal immune response to fetal antigensD. Lissauer — 2012
• The immunomodulating activities of resveratrol glucosides in humans.Hilary McMillan, Martyn Clark, Ross Woods — 2011
• Intracellular interferon-γ staining analysis of donor-specific T-cell responses in liver transplant recipients.Jonathan Spring — 2012
• Expression of the T‐cell regulatory marker FOXP3 in primary cutaneous large B‐cell lymphoma tumour cellsRafael Alcácer Guirao — 2012
• Is Multiple Sclerosis an Autoimmune Disease?John C. Wilcox — 2012
• The split nature of tumor-infiltrating leukocytesHendyat Soetopo — 2012
• FOXP3, CBLB and ITCH gene expression and cytotoxic T lymphocyte antigen 4 expression on CD4+CD25high T cells in multiple sclerosisJulian Shehu, Fatos Harizaj, Ardian Maçi — 2012
• Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survivalMario Boero Vargas — 2012
• Enhanced Suppression of the Xenogeneic T-Cell Response In Vitro by Xenoantigen Stimulated and Expanded Regulatory T CellsJosé Galindo Lucas — 2014
• Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humansFrédéric Delacoux — 2013
• Increased Frequency of CD4 and CD8 Regulatory T Cells in Individuals under 15 Years with Multibacillary LeprosyDevin Neubrander — 2013
• Adipose tissue‐resident regulatory T cells: phenotypic specialization, functions and therapeutic potentialS. Prakash, B. K. Dhindaw, Sanghamitra Sengupta — 2014
• Systemic immunotoxicity reactions induced by adjuvanted vaccines.K. van Rozen — 2014
• Probiotic ‘glow of health’: it’s more than skin deepZapata Rodríguez, Julián Camilo — 2014
• The immunomodulatory effects of human mesenchymal stem cells on peripheral blood mononuclear cells in ALS patientsA.J. Francis, S Dobbs, R.F. Doering — 2014
• Interpretation of transplant biopsies and immune responses following Treg cell therapyQizhi Tang, Sang‐Mo Kang — 2014
• The selective impact of transgenically expressed glucocorticoid receptor on T cellsB. A. McGregor, R. C. Couchman — 2015
• Proinflammatory T cells and IL-17 stimulate osteoblast differentiation.Dionne Paki — 2016

Related papers

• Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected miceKevin N. Couper, Daniel G. Blount, J. Brian de Souza — 2007
• Alterations of peripheral CD4+CD25+Foxp3+ T regulatory cells in mice with STZ-induced diabetesZhen Yu, Lina Sun, He Liu — 2011
• Avian CD4(+)CD25(+) regulatory T cells: properties and therapeutic applications.Ramesh K. Selvaraj — 2013
• Decrease in Regulatory T-cells and Increase in T Helper 17 Cells in Women With Recurrent Spontaneous AbortionMina Badiee, Mehri Ghafourian, Ata Ghadiri — 2021
• [Changes of CD4 + CD25 + Foxp3 + Regulatory T Cells in Different Stages of COPD and Intervention of Qibai Pingfei Capsules].Hui Jiang, Li Zg, Jia-rong Gao — 2014
• Evaluation of CD4+ CD25+ FoxP3+ regulatory T cells during treatment of patients with brucellosis.Mohammad Reza Hasanjani Roushan, Masomeh Bayani, S Soleimani Amiri — 2016
• Expression of CD4~+CD25~+ regulatory T cell and Foxp3 gene in systemic lupus erythematosusChang‐Lin Wu — 2006
• Frequency of regulatory T cells and its relationship with survival rate in patients with hepatocellular carcinomaShuo Li — 2010
• Change and significance of CD4~+CD25~+FoxP3~+Treg in patients with type 2 diabetes before and after insulin intensive therapyYing Dong — 2010