Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
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Summary
The molecular mechanisms by which forces might act at a distance to induce mechanochemical conversion in the nucleus and alter gene activities are explored.
- Type
- review
- Published
- 2009-01-01
- Cited by
- 1,768
- References
- 105
- OpenAlex
- https://openalex.org/W2071145526
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24000069
Keywords
Mechanotransduction, Nucleus, Cytoplasm, Cytoskeleton, Chemistry
References
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- Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF.
- Association of nuclear matrix antigens with exon-containing splicing complexes
- Local force and geometry sensing regulate cell functions
- Identifying Functional Neighborhoods within the Cell Nucleus: Proximity Analysis of Early S-Phase Replicating Chromatin Domains to Sites of Transcription, RNA Polymerase II, HP1γ, Matrin 3 and SAF-A
- Mechanotransduction in vascular physiology and atherogenesis
- Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export
- Replication and transcription: Shaping the landscape of the genome
- Tensegrity I. Cell structure and hierarchical systems biology
- Mechanical anisotropy of adherent cells probed by a three-dimensional magnetic twisting device.
- Prestress mediates force propagation into the nucleus.
- Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells.
- Inner nuclear membrane proteins: functions and targeting
Cited by
- An in silico future for the engineering of functional tissues and organs
- Balancing forces: architectural control of mechanotransduction
- Nuclear mechanics in differentiation and development.
- Mast Cells Are Required in the Proliferation and Remodeling Phases of Microdeformational Wound Therapy
- Role of Actin Dependent Nuclear Deformation in Regulating Early Gene Expression
- The Role of Mechanical Force and ROS in Integrin-Dependent Signals
- Tissue-Engineered Breast Reconstruction: Bridging the Gap toward Large-Volume Tissue Engineering in Humans
- Informatics-based analysis of mechanosignaling in the laminopathies.
- Unidirectional cell crawling model guided by extracellular cues.
- Nuclear–cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions
- New approaches for understanding the nuclear force balance in living, adherent cells
- Fibronectin Fibrillogenesis Facilitates Mechano-dependent Cell Spreading, Force Generation, and Nuclear Size in Human Embryonic Fibroblasts
- Transcriptional Homeostasis of Oxidative Stress-Related Pathways in Altered Gravity
- Adaptable Fast Relaxing Boronate‐Based Hydrogels for Probing Cell–Matrix Interactions
- Role of nuclear mechanosensitivity in determining cellular responses to forces and biomaterials.
- Molecular Engineering of Pericellular Microniche via Biomimetic Proteoglycans Modulates Cell Mechanobiology
- Cellular Mechanics and Intracellular Organization
- Mechanochemical control of stem cell biology in development and disease: Experimental and theoretical models
- Differential Regulation of Two- and Three-Dimensional Cell Function.
- La migration des cellules et leur sensibilité aux propriétés physiques de la matrice extracellulaire : rôle d'ICAP-1, un régulateur des intégrines et de la contractilité
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