Regional control of cerebral vascular reactivity and oxygen supply in man.
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Summary
Gold electrodes implanted for treatment of psychiatric disorders and intractable epilepsy were used to measure the local oxygen availability (O2a) in the intact brain, suggesting the Bohr shift of the oxyhaemoglobin dissociation curve by metabolic and arterial CO2 determines the cerebral tissue oxygenation during short-lived changes of metabolic rate and respiratory variations.
- Type
- article
- Published
- 1966-12-01
- Cited by
- 145
- References
- 40
- OpenAlex
- https://openalex.org/W2070970879
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39153665
Keywords
Hypercapnia, Oxygen–haemoglobin dissociation curve, Cerebral blood flow, Oxygenation, Oxygen
References
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Cited by
- Brain activity and blood flow velocity changes: a transcranial Doppler study.
- Oxygen Polarography in the Awake Macaque: Bridging BOLD fMRI and Electrophysiology
- Metabolic and hemodynamic oscillations monitored optically in the brain exposed to various pathological states.
- Clinical application of basal regional cerebral blood flow fluctuation measurements by FMRI.
- A link between vasomotion and spontaneous oscillations of oxygen in rat brain.
- A Quest for Meaning in Spontaneous Brain Activity - From fMRI to Electrophysiology to Complexity Science
- Development of Current Concepts of Physiology of Cerebral Circulation: A Comparative Analysis
- Local PO2 and unit activity measured with an oxygen microelectrode from the gerbil cerebral cortex during seizure and EEG suppression.
- The metabolic requirements of functional activity in the human brain: a positron emission tomography study.
- Relationships between Cerebral Blood Flow Dynamics and Bioelectric Activity of the Human Brain in Experimental Acute Hypoxia
- Stimulated Cerebral Blood Flow
- Transcranial near infrared spectroscopy and stimulation of prefrontal cognitive functions in young adults
- THE PATHOPHYSIOLOGY OF OCCLUSIVE CEREBROVASCULAR DISORDERS
- Slow Rhythmic Oscillations within the Human Cranium: Phenomenology, Origin, and Informational Significance
- Bandwidth-Specific Functional Connectivity of Physiological Low Frequency Oscillations in fMRI
- Brain-computer communication based on the dynamics of brain oscillations.
- Event-related slow (DC) potentials in the human brain.
- Neural Basis of Functional Connectivity MRI
- Simultane Erfassung cerebraler Aktivität mittels Dipol-Quellenlokalisation und funktioneller MRT am Beispiel einer somatosensorischen Kategorisierungsaufgabe
- Supplementary motor area and other cortical areas in organization of voluntary movements in man.
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