Tris (Hydroxymethyl) Aminomethane (THAM) Induced Stimulation of Insulin Release by Islets of Langerhans Previously Isolated from Rat Pancreas

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Summary

It is postulated that THAM molecules penetrate and act at intracellular loci to induce insulin release, possibly by chelating Zn complexed with insulin in beta cell granules.

Type
article
Published
1970-08-01
Cited by
9
References
16

Keywords

Tris, Hydroxymethyl, Insulin, Chemistry, Bicarbonate

References

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