Familial gastric cancer: genetic susceptibility, pathology, and implications for management.
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- Type
- review
- Published
- 2015-02-01
- Cited by
- 350
- References
- 83
- OpenAlex
- https://openalex.org/W2070758971
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1976624
Keywords
Medicine, Cancer, Familial adenomatous polyposis, CDH1, Cancer syndrome
References
- Convex Total Variation Denoising of Poisson Fluorescence Confocal Images With Anisotropic Filtering
- E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer.
- BRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarian.
- Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
- E-cadherin germline mutations in familial gastric cancer
- Complementary molecular approaches reveal heterogeneous CDH1 germline defects in Italian patients with hereditary diffuse gastric cancer (HDGC) syndrome
- Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.
- Pregnancy after prophylactic total gastrectomy
- Histopathological and molecular analysis of gastrectomy specimens from hereditary diffuse gastric cancer patients has implications for endoscopic surveillance of individuals at risk
- Therapeutic targets associated to E-cadherin dysfunction in gastric cancer
- Germline Mutations in MAP3K6 Are Associated with Familial Gastric Cancer
- Risk-reducing Total Gastrectomy for Germline Mutations in E-cadherin (CDH1): Pathologic Findings With Clinical Implications
- A high frequency of BRCA2 gene mutations in Polish families with ovarian and stomach cancer
- Loss of E‐cadherin in mouse gastric epithelial cells induces signet ring‐like cells, a possible precursor lesion of diffuse gastric cancer
- Gastric cancer: New genetic developments
- Identification of genes related to a synergistic effect of taxane and suberoylanilide hydroxamic acid combination treatment in gastric cancer cells
- Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
- E‐cadherin dysfunction in gastric cancer ‐ Cellular consequences, clinical applications and open questions
- Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer.
- Clinical utility gene card for: Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) - update 2012
Cited by
- Current Perspectives on Gastric Cancer
- Current perspectives toward the identification of key players in gastric cancer microRNA dysregulation
- Hereditary Gastric Cancer Syndromes.
- Is there an association between invasive lobular carcinoma of the breast and a family history of gastric cancer?
- Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma.
- Emerging blood-based biomarkers for detection of gastric cancer.
- Pathogenesis of Gastric Cancer
- Hereditary diffuse gastric cancer syndrome: improved performances of the 2015 testing criteria for the identification of probands with a CDH1 germline mutation
- MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail
- Hereditary gastrointestinal cancer
- Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies
- Clinical impact of tumour biology in the management of gastroesophageal cancer
- Lauren classification and individualized chemotherapy in gastric cancer
- Clinicopathologic Features and Germline Sequence Variants in Young Patients (⩽40 Years Old) With Pancreatic Ductal Adenocarcinoma
- Quantification of topological features in cell meshes to explore E-cadherin dysfunction
- Genomic and epigenomic heterogeneity in molecular subtypes of gastric cancer.
- Challenges of deciphering gastric cancer heterogeneity.
- The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature.
- Effect of World Health Organization (WHO) Histological Classification on Predicting Lymph Node Metastasis and Recurrence in Early Gastric Cancer
- Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future.
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