Altered Specificity in DNA Binding by the lac Repressor: A Mutant lac Headpiece that Mimics the gal Repressor

Keywords

Lac repressor, Repressor, lac operon, Mutant, Operator (biology)

References

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Cited by

• The natural DNA bending angle in the lac repressor headpiece-O1 operator complex is determined by protein-DNA contacts and water release.Elisabeth Nordlohne — 2012
• Fitness landscapes of gene regulation in variable environmentsFrank J. Poelwijk — 2008
• The lac Operon: Fluctuations, Growth and EvolutionD. J. Kiviet — 2010
• The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition.Devashish Das, Gert E. Folkers, Marc van Dijk — 2012
• The HhH domain of the human DNA repair protein XPF forms stable homodimersDevashish Das, Konstantinos Tripsianes, Nicolaas G.J. Jaspers — 2007
• Local Gene Regulation Details a Recognition Code within the LacI Transcriptional Factor FamilyFrancisco M. Camas, Eric J. Alm, Juan F. Poyatos — 2010
• Functional rules for lac repressor–operator associations and implications for protein–DNA interactionsLeslie Milk, Robert Daber, Mitchell Lewis — 2010
• Combinatorial targeting of ribbon–helix–helix artificial transcription factors to chimeric recognition sitesMassimiliano Zampini, Finbarr Hayes — 2012
• Empirical fitness landscapes reveal accessible evolutionary pathsFrank J. Poelwijk, Daniel J. Kiviet, Daniel Weinreich — 2007
• Develop reusable and combinable designs for transcriptional logic gatesJian Zhan, Bo Ding, Rui Ma — 2010
• Information-driven protein–DNA docking using HADDOCK: it is a matter of flexibilityMarc van Dijk — 2006
• Insights into the DNA cleavage mechanism of human LINE‐1 retrotransposon endonucleaseKonstantinos Repanas, Gloria Fuentes, Serge X. Cohen — 2009
• Switching DNA-binding specificity by unnatural amino acid substitutionAtanu Maiti — 2005
• Using evolutionary information to find specificity-determining and co-evolving residues.Grigory Kolesov, Leonid A. Mirny — 2009
• Structural characterization of meningococcal vaccine antigen NadA and of its transcriptional regulator NadR in ligand-bound and free forms.Alessia Liguori — 2016
• The cost of evolved constitutive lac gene expression is usually, but not always, maintained during evolution of generalist populationsKelly N. Phillips, Tim F. Cooper — 2021
• Alignment of major-groove hydrogen bond arrays uncovers shared information between different DNA sequences that bind the same proteinJacklin Sedhom, Jason M. Kinser, Lee A. Solomon — 2022
• Identification of critical amino acids in the DNA binding domain of LuxO: Lessons from a constitutive active LuxOShradha Surin, Richa Singh, Manpreet Kaur — 2024
• Local Gene Regulation Details a Recognition Code for the LacI Transcriptional Factor Family Text S 1Francisco M. Camas, E. Alm, J. F. Poyatos — 2010

Related papers

• Radiation Abolishes Inducer Binding to Lactose RepressorNathalie Gillard, M. Spotheim-Maurizot, Michel Charlier — 2005
• Feedback Regulation of Lac Repressor Expression in Escherichia coliStefan Oehler — 2009
• The three operators of the lac operon cooperate in repression.Stefan Oehler, Elisabeth R. Eismann, Helmut Krämer — 1990
• Lac repressor-operator complex.Michele A. Kercher, Ponzy Lu, Mitchell Lewis — 1997
• Conformational transitions of the lac repressor from Escherichia coli.Felicia Y.-H. Wu, Pradip K. Bandyopadhyay, Cheng-Wen Wu — 1976
• Lac repressor can be fused to β-galactosidaseBenno Müller‐Hill, Jürgen Kania — 1974
• THE NON-INDUCIBILITY OF REPRESSOR FORMATION.Aaron Novick, Joan Medved McCoy, John R. Sadler — 1965
• Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and InducerMitchell Lewis, Geoffrey Chang, Nancy C. Horton — 1996
• lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells.Myles Brown, James Figge, Ulla Hansen — 1987