Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways

Keywords

Cell cycle, Apoptosis, Cell cycle checkpoint, Biology, Cell biology

References

• Analysis of the ATM protein in wild-type and ataxia telangiectasia cells.Nicholas D. Lakin, Peter Weber, Tatjana Stanković — 1996
• Antibodies: A Laboratory ManualE. Harlow, David P. Lane — 1988
• Participation of p53 protein in the cellular response to DNA damage.Michael B. Kastan, Onyinye Onyekwere, D Sidransky — 1991
• Dual roles of ATM in the cellular response to radiation and in cell growth control.Yang Xu, David Baltimore — 1996
• The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage.Kevin D. Brown, Yael Ziv, Sunanda Sadanandan — 1997
• Radiation-induced cell cycle arrest compromised by p21 deficiencyJames Brugarolas, Chitra Chandrasekaran, Jeffrey I. Gordon — 1995
• Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiationRathinasamy Baskaran, Lauren D. Wood, Laura Whitaker — 1997
• The Product of the ATM Gene Is a 370-kDa Nuclear Phosphoprotein*Gang Chen, Eva Y.-H.P. Lee — 1996
• A novel form of Epstein-Barr virus latency in normal B cells in vivo.E M Miyashita, Bin Yang, K. M. C. Lam — 1995
• A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry — 1992
• Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?Xin Lü — 1993
• Sequence-specific transcriptional activation is essential for growth suppression by p53.Jennifer A. Pietenpol, Takashi Tokino, Sam Thiagalingam — 1994
• WAF1, a potential mediator of p53 tumor suppression.Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu — 1993
• atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicityChristoph Westphal, Sheldon Rowan, Cornelius Schmaltz — 1997
• Improved method for computing potential doubling time from flow cytometric data.R. Allen White, Nicholas H. A. Terry, Marvin L. Meistrich — 1990
• Tumor suppressor p53 is a direct transcriptional activator of the human bax gene.Toshiyuki Miyashita, John C. Reed — 1995
• Atm-deficient mice: a paradigm of ataxia telangiectasia.Carrolee Barlow, Shinji Hirotsune, Richard Paylor — 1996
• Thymocyte apoptosis induced by p53-dependent and independent pathwaysAlan R. Clarke, Colin A. Purdie, David J. Harrison — 1993
• p53 is required for radiation-induced apoptosis in mouse thymocytesScott W. Lowe, Earlene M. Schmitt, Sallie W. Smith — 1993
• Tumor spectrum analysis in p53-mutant mice.Tyler Jacks, Lee Ann Remington, Bart O. Williams — 1994

Cited by

• The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest.久雄 腰原 — 2000
• Molecular evolution of the p53 network in reptilesShikha Parsai — 2013
• Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotidesStéphane Anglès — 2007
• ATM dependent apoptosis in the nervous systemYoungsoo Lee, Peter J. McKinnon — 2000
• β-elemene enhances both radiosensitivity and chemosensitivity of glioblastoma cells through the inhibition of the ATM signaling pathway.Siwei Liu, Lei Zhou, Yongshun Zhao — 2015
• Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development.Alexander J.R. Bishop, M. Christine Hollander, Béla Kosaras — 2003
• ATM: genome stability, neuronal development, and cancer cross paths.Yosef Shiloh, Michael B. Kastan — 2001
• Ionizing Radiation-Induced DNA Damage, Response, and RepairWil L. Santivasi, Fen Xia — 2014
• Abnormal myo-inositol and phospholipid metabolism in cultured fibroblasts from patients with ataxia telangiectasia.Mark A. Yorek, Joyce A. Dunlap, Arturo Manzo-Fontes — 1999
• Caffeine Sensitizes Human H358 Cell Line to p53-mediated Apoptosis by Inducing Mitochondrial Translocation and Conformational Change of BAX Protein*Laurence Dubrez, Jean‐Luc Coll, Amandine Hurbin — 2001
• Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrestGen Sheng Wu, Timothy F. Burns, E. Robert McDonald — 1999
• Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic responseMelissa T. Jack, Richard A. Woo, Atsushi Hirao — 2002
• Apoptosis regulators and their role in tumorigenesis.Martin Zörnig, Anne‐Odile Hueber, Wiebke Baum — 2001
• Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.Carrolee Barlow, Phyllis A. Dennery, Mark K. Shigenaga — 1999
• Mechanisms of p53-mediated apoptosisStewart Bates, Karen H. Vousden — 1999
• Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.Michael Ollmann, Lynn Young, Charles J. Di Como — 2000
• The cellular response to p53: the decision between life and deathRonit Vogt Sionov, Ygal Haupt — 1999
• Roles of BRCA1 and its interacting proteinsChu‐Xia Deng, Steven G. Brodie — 2000
• Hereditäre Karzinomsyndrome in der FrauenheilkundeMatthias W. Beckmann, Bettina Kuschel, Rita K. Schmutzler — 1998
• Gene amplification in fibroblasts from ataxia telangiectasia (AT) patients and in X-ray hypersensitive AT-like Chinese hamster mutants.Chiara Mondello — 2001

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