Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

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Summary

The use of fluorescence in situ hybridization for chromosome classification and detection of chromosome aberrations is described and chromosomes in human-hamster hybrid cell lines were intensely and uniformly stained in metaphase spreads and interphase nuclei when human genomic DNA was used as a probe.

Type
article
Published
1986-05-01
Cited by
3,250
References
1
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Open access

Keywords

Metaphase, Molecular biology, Biology, Hybridization probe, Interphase

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