Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles.
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Summary
The synthesis of trastuzumab-functionalized pegylated iron oxide nanoparticles is presented and an FTIR-based approach is provided to gain a direct evidence of the actual conservation of the native structure of conjugated antibody.
- Type
- article
- Published
- 2011-02-10
- Cited by
- 33
- References
- 24
- OpenAlex
- https://openalex.org/W2057980589
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12415626
Keywords
Conjugated system, Nanoparticle, Selectivity, Antibody, Combinatorial chemistry
References
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Cited by
- Protein-assisted one-pot synthesis and biofunctionalization of spherical gold nanoparticles for selective targeting of cancer cells.
- Biomedical Applications of Trastuzumab: As a Therapeutic Agent and a Targeting Ligand
- Covalent bridging of surface functionalized Fe3O4 and YPO4:Eu nanostructures for simultaneous imaging and therapy.
- Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications
- Orientation and density control of bispecific anti-HER2 antibody on functionalized carbon nanotubes for amplifying effective binding reactivity to cancer cells.
- Delivering Colloidal Nanoparticles to Mammalian Cells: A Nano–Bio Interface Perspective
- A prospective cancer chemo-immunotherapy approach mediated by synergistic CD326 targeted porous silicon nanovectors
- Barbituric acid-based magnetic N-halamine nanoparticles as recyclable antibacterial agents.
- Biotechnological approaches toward nanoparticle biofunctionalization.
- Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer
- Dependence of nanoparticle-cell recognition efficiency on the surface orientation of scFv targeting ligands.
- Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media
- Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition.
- Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells.
- Synthesis and Biofunctionalization of Novel Composite Nanocarriers for Targeted Detection and Treatment of Malignant Cells
- Peptide conjugation: before or after nanoparticle formation?
- Targeted approaches for HER2 breast cancer therapy: News from nanomedicine?
- Extremophiles: Applications in Nanotechnology
- Synthesis, Characterization, and Selective Delivery of DARPin-Gold Nanoparticle Conjugates to Cancer Cells.
- Targeted Bifunctional Proteins and Hybrid Nanoconstructs for Cancer Diagnostics and Therapies
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