DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.
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Summary
Data suggest that any sequence-specific de novo methylation mediated by Dnmt1 is either under the control of regulatory factors that interact with DnMT1, or is cued by alternative secondary structures in DNA.
- Type
- article
- Published
- 1997-07-18
- Cited by
- 400
- References
- 56
- Access
- Open access
- OpenAlex
- https://openalex.org/W2056521900
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42547847
Keywords
Methyltransferase, Biology, DNA methylation, DNA methyltransferase, DNMT1
References
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- Isolation and expression of a chicken DNA methyltransferase cDNA.
- Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.
- Transcriptional repression by methylation of CpG
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- Creation of genomic methylation patterns
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- The flip side of DNA methylation.
- Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
- De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.
Cited by
- Establishment and maintenance of DNA methylation patterns in mammals.
- Genomic Imprinting and Assisted Reproductive Technology: Connections and Potential Risks
- Implications of epigenetics and genomic imprinting in assisted reproductive technologies
- Dnmt1 structure and function.
- Targeting DNA methyltransferase in cancer
- An investigation of the contribution of cigarette smoking and human papillomavirus infection to the epigenetic modulation of cellular genes in cervical epithelium
- Breast cancer and the importance of early life nutrition.
- Mechanistic and functional links between histone methylation and DNA methylation.
- Nuclear architecture and structural dynamics - molecular basis of chromatin remodeling induced by human ISWI machines -
- Dynamics of DNA methylation in differentiating hematopoietic cells
- Down-regulation of DNA Methyltransferase 1 by Peroxisome Proliferator-Activated Receptor Gamma in Hepatic Stellate Cells
- Stress-induced genomic responses in Arabidopsis thaliana and Saccharomyces cerevisiae
- DNA methylation and histone modifications in patients with cancer: potential prognostic and therapeutic targets.
- Les nouvelles technologies de l’assistance médicale à la procréation (amp) et la qualité des gamètes et des embryons : évaluation de l’épigénome
- DNA-Methylierung als epigenetischer Regulator von fünf Genen im nicht-kleinzelligen Lungenkarzinom (NSCLC)
- The role of DNA methyltransferases in fetal programming
- Investigating the regulation of c-Fes non-receptor tyrosine kinase activation and gene expression
- DNA methylation during early mammalian development
- Influence of CpG islands on chromatin structure
- Phase I and Pharmacologic Study of the Human DNA Methyltransferase Antisense Oligodeoxynucleotide MG98 given as a 21-day Continuous Infusion Every 4 Weeks
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