Assessment of the extent of variation in influenza A virus cytotoxic T-lymphocyte epitopes by using virus-specific CD8+ T-cell clones.
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Summary
To assess the extent of variation in CTL epitopes during influenza A virus evolution, 304 CTL clones derived from six study subjects were obtained with specificity for an influenza A/H3N2 virus isolated in 1981 and the frequency of the CTL clone that failed to recognize a more recent influenza virus strain isolated in 2003 was determined.
- Type
- article
- Published
- 2007-02-01
- Cited by
- 57
- References
- 30
- OpenAlex
- https://openalex.org/W2052483994
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1897605
Keywords
CTL*, Epitope, Virology, Biology, Cytotoxic T cell
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Cited by
- Killer T cells in influenza.
- LIVE-ATTENUATED VACCINES AGAINST INFLUENZA VIRUSES AND ROLE OF NS1 IN HOST RESPONSE
- Phylogenetic analysis of swine influenza viruses isolated from humans in Alma-Ata, Kazakhstan
- ROLE OF VIRAL AND HOST FACTORS IN INFLUENZA VIRUS MEDIATED INHIBITION OF INTERLEUKIN-23
- Role of the host genetic variability in the influenza A virus susceptibility.
- DIFFERENTIAL INNATE IMMUNE RESPONSES CORRELATE WITH THE CONTRASTING PATHOGENICITY OF THE EQUINE H7N7 INFLUENZA VIRUS DEMONSTRATED IN HORSES AND BALB/C MICE
- FATT‐CTL assay for detection of antigen‐specific cell‐mediated cytotoxicity
- Positive Selection in CD8+ T-Cell Epitopes of Influenza Virus Nucleoprotein Revealed by a Comparative Analysis of Human and Swine Viral Lineages
- The evolution of human influenza A viruses from 1999 to 2006: A complete genome study
- Targets for the Induction of Protective Immunity Against Influenza A Viruses
- Phenotypic differences in viral immune escape explained by linking within-host dynamics to host-population immunity
- Epistatically Interacting Substitutions Are Enriched during Adaptive Protein Evolution
- Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease
- T-cell immunity to influenza A viruses.
- Correlates of protection: novel generations of influenza vaccines.
- DNA-Vaccine Platform Development Against H1N1 Subtype of Swine Influenza A Viruses
- Infection of HLA-DR1 Transgenic Mice with a Human Isolate of Influenza A Virus (H1N1) Primes a Diverse CD4 T-Cell Repertoire That Includes CD4 T Cells with Heterosubtypic Cross-Reactivity to Avian (H5N1) Influenza Virus
- Consequences of suboptimal priming are apparent for low‐avidity T‐cell responses
- Induction of Virus-Specific Cytotoxic T Lymphocytes as a Basis for the Development of Broadly Protective Influenza Vaccines
- Return of inactivated whole‐virus vaccine for superior efficacy
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