Three‐dimensional, sequence order‐independent structural comparison of a serine protease against the crystallographic database reveals active site similarities: Potential implications to evolution and to protein folding
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Summary
An enhancement over the previously developed technique is described, which considerably reduces the complexity of the algorithm and results in an extremely fast technique to comparisons of 3‐dimensional structures.
- Type
- article
- Published
- 1994-05-01
- Cited by
- 100
- References
- 21
- Access
- Open access
- OpenAlex
- https://openalex.org/W2048792959
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:35930516
Keywords
Subtilisin, Serine, Pairwise comparison, Proteases, Trypsin
References
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- Convergence of active center geometries.
- Crystallographic refinement of the structure of actinidin at 1.7 Å resolution by fast Fourier least‐squares methods
- Common spatial arrangements of backbone fragments in homologous and non-homologous proteins.
- Identification of tertiary structure resemblance in proteins using a maximal common subgraph isomorphism algorithm.
- Molecular surface recognition by a computer vision-based technique.
- Use of techniques derived from graph theory to compare secondary structure motifs in proteins.
- Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures.
- The aromatic substrate binding site in subtilisin BPN' and its resemblance to chymotrypsin.
- Molecular surface representations by sparse critical points
- Comparison of protein structures.
Cited by
- Detection of protein three-dimensional side-chain patterns: new examples of convergent evolution.
- Comparing Graph Representations of Protein Structure for Mining Family-Specific Residue-Based Packing Motifs
- Mining Spatial Motifs from Protein Structure Graphs
- Delineating Structural Characteristics of Viral Capsid Proteins Critical for Their Functional Assembly.
- Predicting protein-ligand and protein-peptide interfaces
- Computational approaches for identifying inhibitors of protein interactions
- Revealing divergent evolution, identifying circular permutations and detecting active-sites by protein structure comparison
- Overview of Protein Structural and Functional Folds
- Computational methods for the structural alignment of molecules
- Structural genomics and its importance for gene function analysis
- A hybrid clustering of protein binding sites
- Computergestützte Strukturbestimmung biochemischer Komplexe durch einen Fuzzy Logic-basierten Algorithmus
- Efficient and scalable geometric hashing method for searching protein 3D structures
- Protein-protein interfaces: architectures and interactions in protein-protein interfaces and in protein cores. Their similarities and differences.
- Similarity recognition of molecular structures by optimal atomic matching and rotational superposition
- Structure Comparison and Structure Patterns
- Using a library of structural templates to recognise catalytic sites and explore their evolution in homologous families.
- Conformational Studies Using Molecular Mechanics on Model Peptides with 1-Aminocycloalkane 1-Carboxylic Acid Residues
- Accurate Classification of Protein Structural Families Using Coherent Subgraph Analysis
- Trypsin Gene Expression by Quantitative In Situ Hybridization in Carnivorous and Herbivorous Prickleback Fishes (Teleostei: Stichaeidae): Ontogenetic, Dietary, and Phylogenetic Effects
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