Species specificity of insulin binding and insulin receptor protein tyrosine kinase activity.

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Summary

Data suggest that MA 10 is directed against a region of the insulin receptor that is in between the insulin-binding domain and the beta-subunit and that in human, but not rat, tissues, this region is involved in insulin binding.

Type
article
Published
1987-12-01
Cited by
6
References
26

Keywords

Autophosphorylation, Insulin receptor, IRS2, Internal medicine, GRB10

References

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