Cell death by apoptosis and its protective role against disease.
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Summary
The description of apoptosis as cellular 'suicide', the functional opposite of mitosis, is now attracting more attention and is providing new insights into the pathophysiology of a variety of diseases, and suggesting new therapeutic strategies.
- Type
- review
- Published
- 1992-01-01
- Cited by
- 436
- References
- 45
- OpenAlex
- https://openalex.org/W2048133075
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4290784
Keywords
Apoptosis, Programmed cell death, Mitosis, Disease, Cell
References
- Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
- Apoptosis induced by cold shock in vitro is dependent on cell growth phase.
- Effect of transforming growth factor beta on cell death of cultured rat hepatocytes.
- Cell death: the significance of apoptosis.
- Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.
- Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.
- Identification of mRNAs associated with programmed cell death in immature thymocytes
- Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma.
- Facts and theories concerning the mechanisms of carcinogenesis
- Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.
- Cell death induced in a murine mastocytoma by 42-47 degrees C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load.
- Treatment with antiandrogens induces an androgen‐repressed gene in the rat ventral prostate
- Monoclonal antibody-mediated tumor regression by induction of apoptosis.
- Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis
- Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis
- Degenerative changes, DNA synthesis and mitotic activity in rat liver following single exposure to diethylnitrosamine.
- Cytotoxic action of hormones of the adrenal cortex according to the method of unstained cell counts.
- bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship.
- Programmed death of autoreactive thymocytes
- Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments--I. Single agent regimen.
Cited by
- Cocaine‐induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes
- Induction of apoptosis and cathepsin D in limbs exposed in vitro to an activated analog of cyclophosphamide.
- Hypoxia and brain development.
- Abnormalities of protein kinases in neurodegenerative diseases.
- Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease.
- Recognizing death: liver phagocytosis of apoptotic cells.
- Cell proliferation, apoptosis, and apoptosis inhibition in malignant transformation of sinonasal inverted papilloma
- Tissue transglutaminase: a candidate effector element of physiological cell death.
- Myocyte Cell Loss in Ischemic Cardiomyopathy: Role of Apoptosis
- Neuronal anion exchange proteins in Alzheimer's disease pathology.
- Nigrostriatal neuronal death in Parkinson's disease--a passive or an active genetically-controlled process?
- CD95/CD95L-mediated apoptosis of the hepatic stellate cell. A mechanism terminating uncontrolled hepatic stellate cell proliferation during hepatic tissue repair.
- A thioester analogue of an amino acetylenic aldehyde is a suicide inhibitor of aldehyde dehydrogenase and an inducer of apoptosis in mouse lymphoid cells overexpressing the bcl2 gene.
- Comments on "What is a tumor promoter?".
- Demonstration of Testicular Apoptosis in Human Male Infertility States Using a DNA Laddering Technique
- Programmed cell death and mammary neoplasia.
- Calcium Channel Blockers and the Risk of Cancer: A Preclinical Assessment
- Role of nitric oxide in the induction of apoptosis by smokeless tobacco extract
- Growth arrest and induction of apoptosis in breast cancer cells by antisense depletion of protein kinase A-RIα subunit: p53-independent mechanism of action
- Gold nanoparticle-biomolecule conjugates : synthesis, properties, cellular interactions and cytotoxicity studies
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