PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments
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Summary
PAL2NAL is a web server that constructs a multiple codon alignment from the corresponding aligned protein sequences that can be used to evaluate the type and rate of nucleotide substitutions in coding DNA for a wide range of evolutionary analyses.
- Type
- article
- Published
- 2006-07-01
- Cited by
- 3,148
- References
- 12
- Access
- Open access
- OpenAlex
- https://openalex.org/W2046183549
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15842103
Keywords
Biology, Stop codon, Genetics, Pseudogene, Computational biology
References
- PAML: a program package for phylogenetic analysis by maximum likelihood
- transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
- A codon-based model of nucleotide substitution for protein-coding DNA sequences.
- Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis.
- Molecular evolution of mRNA: A method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4
- Dynamite: A Flexible Code Generating Language for Dynamic Programming Methods Used in Sequence Comparison
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
- RevTrans: multiple alignment of coding DNA from aligned amino acid sequences
- The Bioperl toolkit: Perl modules for the life sciences.
- A genome-wide survey of human pseudogenes.
Cited by
- Molecular evolution of the p53 network in reptiles
- Identification and characterization of type III effector proteins in plant-associated bacteria
- The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals
- Molecular biology, genetics and biochemistry of the repulsive guidance molecule family
- A Computational Study of Elongation Factor G (EFG) Duplicated Genes: Diverged Nature Underlying the Innovation on the Same Structural Template
- Systematic analysis of plant-specific B3 domain-containing proteins based on the genome resources of 11 sequenced species
- Early Events in the Evolution of Spider Silk Genes
- The salmonid myostatin gene family: a novel model for investigating mechanisms that influence duplicate gene fate
- Root parasitic plant Orobanche aegyptiaca and shoot parasitic plant Cuscuta australis obtained Brassicaceae-specific strictosidine synthase-like genes by horizontal gene transfer
- Bioinformatic Analysis Reveals Genome Size Reduction and the Emergence of Tyrosine Phosphorylation Site in the Movement Protein of New World Bipartite Begomoviruses
- Complete Chloroplast Genome Sequence of Tartary Buckwheat (Fagopyrum tataricum) and Comparative Analysis with Common Buckwheat (F. esculentum)
- Differential Functional Constraints Cause Strain-Level Endemism in Polynucleobacter Populations
- Evolution of gremlin 2 in cetartiodactyl mammals: gene loss coincides with lack of upper jaw incisors in ruminants
- Resolution of deep eudicot phylogeny and their temporal diversification using nuclear genes from transcriptomic and genomic datasets.
- Genome-wide analysis of the CCCH zinc finger family identifies tissue specific and stress responsive candidates in chickpea (Cicer arietinum L.)
- Selective pressure on the protein-coding genes of the pufferfish is correlated with phenotypic traits.
- High intraspecific diversity of Restorer‐of‐fertility‐like genes in barley
- cRegions—a tool for detecting conserved cis-elements in multiple sequence alignment of diverged coding sequences
- Identification of Phytocyanin Gene Family in Legume Plants and their Involvement in Nodulation of Medicago truncatula.
- Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum
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