Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan--a review.

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Summary

Alginate, being an anionic polymer with carboxyl end groups, is a good mucoadhesive agent and cross-linked alginate has more capacity to retain the entrapped drugs and mixing of alginates with other polymers such as neutral gums, chitosan, and eudragit have been found to solve the problem of drug leaching.

Type
review
Published
2006-08-10
Cited by
1,963
References
179

Keywords

Chitosan, Chemistry, Self-healing hydrogels, Polymer, Pectin

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