Identification of tissue transglutaminase as the autoantigen of celiac disease
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Summary
Tissue transglutaminase is identified as the unknown endomysial autoantigen of celiac disease, and gliadin is a preferred substrate for this enzyme, giving rise to novel antigenic epitopes.
- Type
- article
- Published
- 1997-06-29
- Cited by
- 2,094
- References
- 36
- OpenAlex
- https://openalex.org/W2043856196
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20033968
Keywords
Tissue transglutaminase, Endomysium, Gliadin, Medicine, Coeliac disease
References
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Cited by
- Strongly positive tissue transglutaminase antibody assays without celiac disease.
- Survey of gastroenterologists on the diagnosis and treatment of adult patients with celiac disease in British Columbia.
- Evaluation of T-lymphocyte subtypes in the diagnosis of celiac disease.
- Comparison of IgA endomysium antibody and IgA tissue transglutaminase antibody in celiac disease.
- Autoantibodies in coeliac disease: tissue transglutaminase—guilt by association?
- Human recombinant tissue transglutaminase ELISA: an innovative diagnostic assay for celiac disease
- T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
- Characterization of a Subgroup of Patients With Dermatitis Herpetiformis With Nonclassical Histologic Features.
- Gut Mucosal Immunity to Tissue Transglutaminase in Untreated Celiac Disease and Other Gastrointestinal Disorders
- T-independent IgA responses to microbial polysaccharides.
- Enfermedad celíaca en una población de riesgo en la provincia de Tucumán
- Anti-tissue transglutaminase antibodies in inflammatory bowel disease: new evidence
- Anti-tissue transglutaminase antibodies and their role in the investigation of coeliac disease
- Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.
- Two-year follow-up of anti-transglutaminase autoantibodies among celiac children on gluten-free diet: Comparison of IgG and IgA
- Humoral immune response to tissue transglutaminase is related to epithelial cell proliferation in celiac disease.
- Mucosal tissue transglutaminase expression in celiac disease
- Integration of genetic and immunological insights into a model of celiac disease pathogenesis.
- Anti-endomysial Antibody Negative Celiac Disease
- The function of tissue transglutaminase in celiac disease.
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