Inhibitory effect of diazepam on the activity of the hypothalamic-pituitary-adrenal axis in female rats
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Summary
It is suggested that central benzodiazepine receptors, the part of GABA-A macromolecular complex, are involved in diazepam-induced inhibition of the activity of the HPA axis.
- Type
- article
- Published
- 2005-01-01
- Cited by
- 19
- References
- 60
- OpenAlex
- https://openalex.org/W2041913450
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9886834
Keywords
Internal medicine, Endocrinology, Diazepam, GABAA receptor, Bicuculline
References
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- Selective antagonists of benzodiazepines
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- The effects of putative anxiogenic compounds (FG 7142, CGS 8216 and Ro 15-1788) on the rat corticosterone response.
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- Sex differences in the response of rats to drugs affecting GABAergic transmission.
- Central-type benzodiazepine binding sites in rat pituitary gland are of the BZ1 subtype.
- Effect on various putative neurotransmitters on the secretion of corticotrophin-releasing hormone from the rat hypothalamus in vitro-a model of the neurotransmitters involved.
- Reduction in urinary free cortisol during benzodiazepine treatment of panic disorder.
- GABA receptors: are cellular differences reflected in function?
- Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level.
- The fluorimetric determination of corticosterone in rat adrenal tissue and plasma: effect of administering ACTH subcutaneously.
- A comparison of the effects of buspirone and diazepam on plasma corticosterone levels in rat.
Cited by
- Hypothalamic-pituitary-adrenal axis activity, dehydroepiandrosterone sulphate and their relationships with aggression in early and late alcohol withdrawal.
- Effects of diazepam on conflict behaviour and on plasma corticosterone levels in male and female rats
- Alprazolam and oxazepam block the cue-induced reinstatement of extinguished cocaine seeking in rats
- Corticosterone response in the chick separation-stress paradigm.
- Acute anxiogenic-like effects of selective serotonin reuptake inhibitors are attenuated by the benzodiazepine diazepam in BALB/c mice
- Effects of benzodiazepines receptor agonists on the hypothalamic-pituitary-adrenocortical axis.
- Pituitary side effects of old and new drugs
- Neuroregulation of the Hypothalamus-Pituitary-Adrenal (HPA) Axis in Humans: Effects of GABA-, Mineralocorticoid-, and GH-Secretagogue-Receptor Modulation
- The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats
- Neuroendocrine pathways in benzodiazepine dependence: new targets for research and therapy
- Cannabinoids and Their Interactions with Diazepam on Modulation of Serum Corticosterone Concentration in Male Mice
- Relation between Corticotropin-Releasing Hormone Neuron Number in the Hypothalamic Paraventricular Nucleus and Depressive State in Alzheimer’s Disease
- Effects of some psychiatric drugs on corticotropin-releasing factor (CRF) gene expression in mouse hypothalamus cells in vitro
- Nicotine increases behavioral variability on radial arm maze extinction. A preliminary study
- JM-20 potently prevents the onset of caffeine-induced anxiogenic phenotypes in zebrafish (Danio rerio).
- Bridging the gap: The endocannabinoid system as a functional fulcrum for benzodiazepines in a novel frontier of anxiety pharmacotherapy
- GABA neurocircuits controlling the Hypothalamic- Pituitary-Adrenal Axis
- DOSE RELATED ANXIOLYTIC EFFECTS OF DIAZEPAM: RELATION WITH SERUM ELECTROLYTES, PLASMA OSMOLALITY AND SYSTOLIC BLOOD PRESSURE (SBP) IN RATS
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