Heterochromatin protein 1: don't judge the book by its cover!
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Summary
Not only do HP1 isoforms have specific binding sites in both heterochromatic and euchromatic domains but they might also participate in the repression and activation of transcription in both compartments.
- Type
- review
- Published
- 2006-04-01
- Cited by
- 170
- References
- 53
- OpenAlex
- https://openalex.org/W2041659028
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31383945
Keywords
Euchromatin, Heterochromatin, Heterochromatin protein 1, Biology, Genetics
References
- Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation.
- Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location.
- Chromosomal Distribution of Heterochromatin Protein 1 (HP1) in Drosophila: a Cytological Map of Euchromatic HP1 Binding Sites
- Increased phosphorylation of HP1, a heterochromatin-associated protein of Drosophila, is correlated with heterochromatin assembly.
- The effects of chromosome rearrangements on the expression of heterochromatic genes in chromosome 2L of Drosophila melanogaster.
- Mutations in the heterochromatin protein 1 (HP1) hinge domain affect HP1 protein interactions and chromosomal distribution
- XNP-1/ATR-X acts with RB, HP1 and the NuRD complex during larval development in C. elegans.
- Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.
- Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes.
- Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α
- Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin
- Dynamic associations of heterochromatin protein 1 with the nuclear envelope
- Effects of tethering HP1 to euchromatic regions of the Drosophila genome
- Differences in stability of repressor complexes at promoters underlie distinct roles for Rb family members
- Rb targets histone H3 methylation and HP1 to promoters
- Types of visible variations induced by X-rays inDrosophila
- Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3
- Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells
- A Complex with Chromatin Modifiers That Occupies E2F- and Myc-Responsive Genes in G0 Cells
- Position effect variegation in Drosophila is associated with an altered chromatin structure.
Cited by
- Identification and Characterization of Novel Sir3/MeCP2-Chromatin Interactions
- Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
- TRIM involvement in transcriptional regulation.
- Chromatin architecture and the orchestration of gene expression: cell systems to explore epigenetic gene control
- TERMINAL FLOWER2, the Arabidopsis HETEROCHROMATIN PROTEIN1 Homolog, and its Involvement in Plant Development
- PERTURBATION DE LA DYNAMIQUE DE L'HETEROCHROMATINE PAR DES LIGANDS SYNTHETIQUES DU PETIT SILLON DE L'ADN
- Base Excision Repair in Chromatin
- The regulation of preadipocyte differentiation by glucocorticoids
- Heterochromatin composition and function in Drosophila
- The genetics of the sexually dimorphic deaths of the C. elegans CEM neutrons
- Chromatin Flavors: Chromatin composition and domain organization in Drosophila melanogaster
- HP1a/KDM4A is involved in the autoregulatory loop of the oncogene gene c-Jun
- Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans
- Histone Demethylases and Cancer
- Eukaryotic DNA replication in a chromatin context.
- Genome organization of DNA replication timing and its link to chromatin and transcription
- Caractérisation épigénétique du lymphome du manteau
- Identification and characterisation of Mybbp1a as a regulator of rRNA synthesis
- Multivalency governs HP1α association dynamics with the silent chromatin state
- Differential Cooperation between Heterochromatin Protein HP1 Isoforms and MyoD in Myoblasts*
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