Origin of the chloride current in olfactory transduction.
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Summary
In the cilia of amphibian olfactory receptor neurons, odorants elicit a receptor current that has two components: a cationic current through cAMP-gated channels and a Cl- current.
- Type
- article
- Published
- 1993-07-01
- Cited by
- 211
- References
- 33
- OpenAlex
- https://openalex.org/W2040105779
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7530869
Keywords
Current (fluid), Chloride channel, Olfactory receptor, Biophysics, Cationic polymerization
References
- Activation by odorants of cation‐selective conductance in the olfactory receptor cell isolated from the newt.
- Olfactory adenylate cyclase of the rat. Stimulation by odorants and inhibition by Ca2+.
- Single odor-sensitive channels in olfactory receptor neurons are also gated by cyclic nucleotides
- Amiloride analogs inhibit L-type calcium channels and display calcium entry blocker activity.
- The Odorant‐Sensitive Adenylate Cyclase of Olfactory Receptor Cells
- Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl- channels in Xenopus oocytes.
- Histamine directly gates a chloride channel in lobster olfactory receptor neurons.
- Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons
- A cyclic nucleotide-gated conductance in olfactory receptor cilia
- High density cAMP-gated channels at the ciliary membrane in the olfactory receptor cell.
- Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurones.
- Ca2(+)-dependent adaptive properties in the solitary olfactory receptor cell of the newt.
- Odorant-sensitive adenylate cyclase may mediate olfactory reception
- Flufenamic acid, mefenamic acid and niflumic acid inhibit single nonselective cation channels in the rat exocrine pancreas
- Spectrophotometric determination of cation concentrations in olfactory mucus.
- Cyclic AMP links amino acid chemoreceptors to ion channels in olfactory cilia
- The spatial distributions of odorant sensitivity and odorant‐induced currents in salamander olfactory receptor cells.
- Simultaneous recording of [Ca2+]i increases in isolated olfactory receptor neurons retaining their original spatial relationship in intact tissue.
- The response induced by intracellular cyclic AMP in isolated olfactory receptor cells of the newt.
- Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells
Cited by
- Calcium transients in the garter snake vomeronasal organ.
- Inositol 1,4,5-trisphosphate-gated conductance in isolated rat olfactory neurons.
- Transduction mechanisms in vertebrate olfactory receptor cells.
- Outward currents in olfactory receptor neurons activated by odorants and by elevation of cyclic AMP
- Heterologous functional expression system for odorant receptors.
- Molecular and functional anatomy of the mouse olfactory epithelium
- Cyclic Nucleotide-Dependent Pathway Is One of Mechanisms of Olfactory Transduction of Amino Acid Signal in the Carp Cyprinus carpio
- When Animal Housing and Strain Difference Matter: Cellular and Behavioral Studies in Mouse Olfaction
- Calcium‐activated chloride currents in olfactory sensory neurons from mice lacking bestrophin‐2
- Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium
- Developmental expression of the calcium‐activated chloride channels TMEM16A and TMEM16B in the mouse olfactory epithelium
- Anoctamin 2/TMEM16B: a calcium‐activated chloride channel in olfactory transduction
- Lipid regulation of olfactory cyclic nucleotide-gated channels
- Ca2+‐Activated Cl− Channels
- Problemas inversos y cálculo de variaciones: aplicaciones a la biología y al análisis de imágenes
- Voltage- and Ca(2+)-gated currents in zebrafish olfactory receptor neurons.
- Calcium Entry through Cyclic Nucleotide-Gated Channels in Individual Cilia of Olfactory Receptor Cells: Spatiotemporal Dynamics
- Characterization of olfactory receptor gene expression in the olfactory epithelium of larval Xenopus laevis
- An electrophysiological survey of frog olfactory cilia.
- The K+ Channel Gene Ether a Go-Go Is Required for the Transduction of a Subset of Odorants in Adult Drosophila melanogaster
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