Childhood trauma and genetic factors in familial schizophrenia associated with the NOS1AP gene
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Summary
The results suggest that childhood trauma is associated with expression of schizophrenia independent of measured genetic susceptibility and may be a candidate for gene-environment research using genetic variants.
- Type
- article
- Published
- 2010-06-11
- Cited by
- 29
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W2039513481
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20027204
Keywords
Schizophrenia (object-oriented programming), Psychology, Genetics, Psychiatry, Medicine
References
- Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications
- Psychiatric Genetics: Applications in Clinical Practice
- Neurodevelopment, neuroplasticity, and new genes for schizophrenia.
- Children at risk for schizophrenia : a longitudinal perspective
- Sexual abuse histories and sequelae in female psychiatric emergency room patients.
- Evidence for a Role of the NOS1AP (CAPON) Gene in Schizophrenia and Its Clinical Dimensions: An Association Study in a South American Population Isolate
- Longitudinal data analysis for discrete and continuous outcomes.
- Childhood head injury and expression of schizophrenia in multiply affected families.
- Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22.
- INFERENCE AND MISSING DATA
- Reliability of Reports of Violent Victimization and Posttraumatic Stress Disorder Among Men and Women With Serious Mental Illness
- Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11
- Adverse childhood experiences and hallucinations.
- The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder
- The Strength of the Genetic Effect
- The impact of cumulative childhood adversity on young adult mental health: measures, models, and interpretations.
- Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22.
- Early and late neurodevelopmental influences in the prodrome to schizophrenia: contributions of genes, environment, and their interactions.
- Reliability and validity of a measure of sexual and physical abuse histories among women with serious mental illness.
- The reliability of abuse history reports: a comparison of two inquiry formats.
Cited by
- NOS1AP is associated with increased severity of PTSD and depression in untreated combat veterans.
- Childhood Trauma as a Cause of Psychosis: Linking Genes, Psychology, and Biology
- Animal models of gene-environment interaction in schizophrenia: a dimensional perspective
- The effects of childhood abuse on self-reported psychotic symptoms in severe mental illness: Mediating effects of posttraumatic stress symptoms.
- Trauma, psychose, PTSS en de toepassing van EMDR
- Environmental risk factors for schizophrenia: implications for prevention
- Childhood trauma and psychosis.
- Prevalence of bullying victimisation amongst first-episode psychosis patients and unaffected controls
- Catechol-O-methyltransferase (COMT) genotype moderates the effects of childhood trauma on cognition and symptoms in schizophrenia.
- Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era
- The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: further evidence and meta-analysis.
- Childhood Adversities Increase the Risk of Psychosis: A Meta-analysis of Patient-Control, Prospective- and Cross-sectional Cohort Studies
- Childhood trauma, antisocial personality typologies and recent violent acts among inpatient males with severe mental illness: exploring an explanatory pathway.
- Early environmental exposures influence schizophrenia expression even in the presence of strong genetic predisposition
- Childhood adversity in schizophrenia: a systematic meta-analysis
- Neglect and hereditary risk: Their relative contribution to schizophrenia with negative symptomatology
- On the Clinical Applicability and Translation of Genetic Discoveries in Schizophrenia
- The Role of Trauma and Stressful Life Events among Individuals at Clinical High Risk for Psychosis: A Review
- Psychiatric behaviors associated with cytoskeletal defects in radial neuronal migration
- Association between parent mental health and paediatric TBI: epidemiological observations from the 1987 Finnish Birth Cohort
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