A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

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Summary

The development of an improved version of YFP named Venus, which contains a novel mutation, F46L, which at 37°C greatly accelerates oxidation of the chromophore, the rate-limiting step of maturation and will enable fluorescent labelings that were not possible before.

Type
article
Published
2002-01-01
Cited by
2,903
References
15

Keywords

Aequorea victoria, Green fluorescent protein, Yellow fluorescent protein, Fluorescence, Förster resonance energy transfer

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