Effects of amyotrophic lateral sclerosis serum on cultured chick spinal neurons
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Summary
Compared with cultures grown in the presence of serum from healthy controls or patients with other neurologic disorders, ALS serum lowered the level of neurofilament proteins, and effects were similar with or without muscle-derived neurotrophic factors; there was no specificity for motor neurons.
- Type
- article
- Published
- 1986-10-01
- Cited by
- 14
- References
- 21
- OpenAlex
- https://openalex.org/W2039111671
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46666782
Keywords
Amyotrophic lateral sclerosis, Neurofilament, Antibody, Neurotrophic factors, Spinal cord
References
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- The effect of nerve growth factor and its antibodies on neurofilament protein expression in primary cultures of sensory and spinal neurons.
- Neurite-promoting activities for embryonic spinal neurons and their developmental changes in the chick.
- Amyotrophic lateral sclerosis sera applied to cultured motor neurons.
- Effects of amyotrophic lateral sclerosis sera on cultured cholinergic neurons
- Passive transfer experiments in amyotrophic lateral sclerosis.
- Human Skeletal Muscle Cells Synthesise a Neuronotrophic Factor Reactive with Spinal Neurons
- Plasmapheresis with immunosuppression in amyotrophic lateral sclerosis.
- Ganglioside GM1 Does Not Initiate, but Enhances Neurite Regeneration of Nerve Growth Factor‐Dependent Sensory Neurones
- Antibodies to motor nerve terminals: an electrophysiological study of a human myasthenic syndrome transferred to mouse.
- Neuron specific in vitro cytotoxicity of sera from patients with amyotrophic lateral sclerosis
- Inhibition of terminal axonal sprouting by serum from patients with amyotrophic lateral sclerosis.
- Diverse forms of motor neuron diseases.
- Blind studies on the effect of amyotrophic lateral sclerosis sera on motor neurons in vitro.
Cited by
- A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis.
- Protective effect of metabotropic glutamate receptor inhibition on amyotrophic lateral sclerosis-cerebrospinal fluid toxicity in vitro.
- Serum from patients with amyotrophic lateral sclerosis induces the expression of B-50/GAP-43 and neurofilament in cultured rat fetal spinal neurons.
- Motor neuron diseases and amyotrophic lateral sclerosis: research progress
- [Cerebrospinal fluid cytotoxicity in lateral amyotrophic sclerosis].
- Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis
- La citotoxicidad del líquido cefalorraquídeo en la esclerosis lateral amiotrófica
- Motor neuron disease (amyotrophic lateral sclerosis).
- Clinical status of motoneuron disease does not correlate with serum neurotoxicity on cultured neurons
- Cell-cell interactions modulate the responsiveness of PC12 cells to nerve growth factor.
- Neuropharmacology of amyotrophic lateral sclerosis.
- 40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?
- Motor Neuron Disease: The Clinical Syndrome
- Cell-cell interactions modulate the responsiveness of PC 12 cells to nerve growth factor
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