Problems in design of stroke treatment trials.

Keywords

Medicine, Sample size determination, Clinical trial, Stroke (engine), Placebo

References

• The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial. Survey of 71 "negative" trials.克哉 中村, 武洋 越智, 昌昭 松尾 — 1978
• Predicting the outcome of stroke: acute stage after cerebral infarction.Mariette Visser — 1975
• Cerebral blood flow.Marc Vitse — 1966
• Myotonia dystrophica: ventricular arrhythmias, intraventricular conduction abnormalities, atrioventricular block and Stokes-Adams attacks successfully treated with permanent transvenous pacemaker.Stephen D. Clements, Rudolf A. Colmers, J. Willis Hurst — 1976
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• Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral InfarctionRaymond B. Bauer, HENRY TELLEZ — 1973
• Raised intracranial pressure and cerebral blood flowI. H. Johnston, J. O. Rowan — 1974
• Ischemic Cerebral Edema. A ReviewM D O’Brien — 1979
• Familial stroke syndrome associated with mitral valve prolapseG Rice, Derek R. Boughner, C. R. Stiller — 1980
• Familial mitral valve prolapse and myotonic dystrophy.Stephen J. Winters, BERNARD SCHREINER, ROBERT C. GRIGGS — 1976
• Circulatory and metabolic effects of glycerol infusion in patients with recent cerebral infarction.John Stirling Meyer, Yoshiaki Itoh, Shosuke Okamoto — 1975
• The outcome with aggressive treatment in severe head injuries. Part II: acute and chronic barbiturate administration in the management of head injury.Lawrence F. Marshall, R. Wayne Smith, Harvey M. Shapiro — 1979
• A blind controlled trial of dextran 40 in the treatment of ischaemic stroke.W.B. Matthews, J.M. Oxbury, Keith Grainger — 1976
• Statistical controversies in the design of clinical trials—Some personal views*Byron W. Brown — 1980
• Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design.Richard Peto, Malcolm C. Pike, P. Armitage — 1976
• Double-blind study of the effects of dexamethasone on acute stroke.Bernard M. Patten, Jerry Mandel, Bertel Bruun — 1971
• IV. Brain Edema in StrokeRobert Katzman, Raymond A. Clasen, I. Klatzo — 1977
• Regional cerebral blood flow in apoplexy without arterial occlusionOlaf B. Paulson, N. A. Lassen, E Skinhöj — 1970
• Controlled Trial of Aspirin in Cerebral IschemiaWilliam S. Fields, Noreen A. Lemak, Ralph F. Frankowski — 1977

Cited by

• Pharmacological Approaches to the Treatment of Brain and Spinal Cord InjuryDonald G. Stein, Bernhard A. Sabel — 1988
• Tortuosity of terminal arterioles in the basal ganglia is increased in status lacunaris.Esteban S Poni, Boleslaw H. Liwnicz, Yingying Yue — 2003
• The haemorheological features of lacunar strokesR Schneider, N. K�rber, H. Zeumer — 2004
• Discharge destination and motor function outcome in severe stroke as measured by the functional independence measure/function-related group classification system.R. L. Sandstrom, Patricia J. Mokler, Kurtis M. Hoppe — 1998
• Assessment scales for the evaluation of stroke patients.Patrick D. Lyden, L. Hantson — 1998
• The natural history of lacunar infarction: the Oxfordshire Community Stroke Project.John Bamford, Peter Sandercock, Lisa Jones — 1987
• Hemispheric strokes: clinical or surgical management? Intracranial pressure monitoring of a case and review of the literature.Gustavo Adolpho Carvalho, Adolpho Carvalho Filho — 1995
• Clinimetrics in stroke research.Kjell Asplund — 1987
• Are hypertension or cardiac embolism likely causes of lacunar infarction?J. Lodder, John Bamford, Peter Sandercock — 1990
• Custom‐Tailored Hemodilution With Albumin and Crystalloids in Acute Ischemic StrokeH. Goslinga, V. Eijzenbach, J.H.A. Heuvelmans — 1992
• Selective vulnerability of the brain: new insights into the pathophysiology of stroke.Robert C. Collins, Bruce H. Dobkin, Dennis W. Choi — 1989
• Hospital referral of stroke patients: a survey of attitudes in general practice, and consideration of entry times for clinical trials.L. Hantson, J. Gheuens, Luc Tritsmans — 1994
• The Pilot Stroke Data Bank: Definition, Design, and DataSelma C. Kunitz, Cynthia R. Gross, Albert Heyman — 1984
• Variables affecting short-term prognosis in completed strokePatricia H. Davis, Bruce S. Schoenberg — 1985
• Hypertension in acute ischemic strokes. Treat.J. David Spence — 1985
• Toward a uniform assessment of “outcome”.J S Feigenson — 1982
• Evolution and testing of the lacunar hypothesis.John Bamford, Charles Warlow — 1988
• Double-blind randomised trial of intravenous glycerol in acute stroke.Antony Bayer, Manivannan Pathy, Robert G. Newcombe — 1987
• Aromatase activity in adipose tissue from breast quadrants: a link with tumour siteJohn S. O’Neill, Robert A. Elton, W.R. Miller — 1988
• Clinical trials in acute ischemic stroke: Problems in design and interpretation.Harold P. Adams, Robert F. Woolson — 1991

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