The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

Explore this paper's citation graph

Summary

The reconstitution of a pathway that leads to the apoptotic changes in nuclei by using recombinant DNA fragmentation factor (DFF), a heterodimeric protein of 40 and 45 kDa, suggests that DFF40 is sufficient to trigger both DNA fragmentation and chromatin condensation during apoptosis.

Type
article
Published
1998-07-21
Cited by
558
References
31
Access
Open access

Keywords

DNA fragmentation, Apoptotic DNA fragmentation, Chromatin, Fragmentation (computing), Prophase

References

Cited by

Related papers