Neoadjuvant chemotherapy in locally advanced gastric carcinoma--a phase II trial with combined continuous intravenous 5-fluorouracil and bolus cisplatinum.
Explore this paper's citation graph
Summary
It is concluded that neodjuvant chemotherapy is feasible in LAGC, although randomised trials are warranted to demonstrate its efficacy on survival and resection rates.
- Type
- article
- Published
- 1994-01-01
- Cited by
- 78
- References
- 40
- OpenAlex
- https://openalex.org/W2036296388
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27794345
Keywords
Medicine, Linitis plastica, Neutropenia, Chemotherapy, Surgery
References
- Chemotherapy and surgery for locally advanced cancer of the cardia and fundus: Phase II study with methotrexate and 5‐fluorouracil
- Histological Typing of Oesophageal and Gastric Tumours
- Influence of the interval between primary tumor removal and chemotherapy on kinetics and growth of metastases.
- Treatment of locally unresectable cancer of the stomach and pancreas: a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil--an Eastern Cooperative Oncology Group study.
- Evaluation of pre- and postoperative chemotherapy for resectable adenocarcinoma of the esophagus or gastroesophageal junction.
- FAMTX versus etoposide, doxorubicin, and cisplatin: a random assignment trial in gastric cancer.
- Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group.
- Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric adenocarcinoma: results of a phase II trial.
- Gastric cancer: a curable disease in Britain.
- Adenocarcinoma of the stomach: Review of 1,497 cases
- Gastric cancer: A 25‐year review
- Adenocarcinoma of the stomach: areas of failure in a re-operation series (second or symptomatic look) clinicopathologic correlation and implications for adjuvant therapy.
- Has there been any improvement in the staging of gastric cancer?. Findings from the German gastric cancer TNM study group
- Evaluation of gastric adenocarcinoma. Abdominal computed tomography does not replace celiotomy.
- Width of serosal invasion and prognosis in advanced human gastric cancer with special reference to the mode of tumor invasion
- Chi-square tests with one degree of freedom
- Signet ring cell carcinoma of the stomach
- Analysis of survival and local control following surgery for gastric cancer
- Current status of chemotherapy for gastric cancer.
- Factors related to survival following resection for gastric carcinoma. Analysis of 903 cases
Cited by
- Scirrhous cancer of the stomach which survived for more than five years after neoadjuvant chemotherapy with UFT (uracil and tegafur) and cisplatin.
- Adjuvant chemotherapy in gastric adenocarcinomas.
- Surgical Clinics of North America
- Multimodality Therapy for Gastric Cancer
- Neoadjuvant chemotherapy and ongoing-trials.
- A weekly 24-h infusion of high-dose 5-fluorouracil (5-FU)+leucovorin and bi-weekly cisplatin (CDDP) was active and well tolerated in patients with non-colon digestive carcinomas.
- Adjuvant and preoperative chemotherapy for gastric cancer
- Neoadjuvant chemotherapy with S-1 and CDDP in advanced gastric cancer
- Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial
- Neoadjuvant chemotherapy in advanced gastric cancer with non-curative factors: a Phase II study with 5-fluorouracil, leucovorin, and cisplatin
- Neoadjuvant chemotherapy in scirrhous cancer of the stomach using uracil and tegafur and cisplatin.
- Radioquimioterapia neoadyuvante en cáncer gástrico T4 localmente irresecable: Resultados preliminares
- Combined-modality therapy for gastric cancer.
- Advanced gastric carcinoma successfully treated with TS-1 as neoadjuvant chemotherapy
- TS-1 as first-line therapy for gastric linitis plastica: historical control study
- Neoadjuvant therapy for patients with locally advanced gastric carcinoma with etoposide, doxirubicin, and cisplatinum
- Therapy of localized gastric cancer: preoperative and postoperative approaches.
- Histological indications of a favorable prognosis with far-advanced gastric carcinomas after preoperative chemotherapy
- Advances in the treatment of patients with gastric adenocarcinoma
- Neoadjuvant chemotherapy in locally advanced gastric-cancer - preliminary-results of a phase-ii trial with a modified famtx combination.
Related papers
- 5-Fluorouracil vs. epirubicin vs. 5-fluorouracil plus epirubicin in advanced gastric carcinoma
- Concentration of 5-fluorouracil in renal cells from cancer patients administered a mixture of 1-(2-tetrahydrofuryl)-5-fluorouracil and uracil.
- FAC (fluorouracil, doxorubicin, cyclophosphamide) as second line chemotherapy in patients with metastatic breast cancer progressing under FEC (fluorouracil, epirubicin, cyclophosphamide) chemotherapy.
- Different doses of epirubicin associated with fixed doses of cyclophosphamide and 5-fluorouracil: a randomised study in advanced breast cancer.
- Phase II trial of epirubicin, uracil-tegafur and leucovorin (ELV) in advanced gastric cancer
- High Doses of 5-Fluorouracil and Epirubicin with or without Cisplatin in Advanced Gastric Cancer: A Randomized Study
- [Blood level of 5-fluorouracil (5-FU) by oral administration of 1-hexylcarbamoyl-5-fluorouracil (HCFU) and tegafur in patients with hepatocellular carcinoma].
- 5-Fluorouracil derivatives XXIII. Synthesis and antitumor activities of 1-carbamoyl-5-fluorouracils having aromatic ring
- 5-Fluorouracil derivatives XXIII. Synthesis and antitumor activities of 1-carbamoyl-5-fluorouracils having aromatic ring
- 表在性膀胱腫瘍に対する1-hexylcarbamoyl-5-fluorouracil (HCFU)および1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur)剤内服による再発防止効果の比較検討