Isocitrate dehydrogenase mutation is associated with tumor location and magnetic resonance imaging characteristics in astrocytic neoplasms
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Summary
The results of the current study suggested that the prolonged survival of patients with IDH-mutated gliomas is primarily due to a less aggressive biological behavior according to tumor site and MRI features.
- Type
- article
- Published
- 2014-03-28
- Cited by
- 156
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W2035855834
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16269008
Keywords
Isocitrate dehydrogenase, Magnetic resonance imaging, Oncogene, Molecular medicine, IDH1
References
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- Malignant gliomas in adults.
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- Apparent diffusion coefficients in oligodendroglial tumors characterized by genotype
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis
- IDH mutations occur frequently in Chinese glioma patients and predict longer survival but not response to concomitant chemoradiotherapy in anaplastic gliomas.
- Reclassification of oligoastrocytomas by loss of heterozygosity studies
- An analysis of image texture, tumor location, and MGMT promoter methylation in glioblastoma using magnetic resonance imaging
- The classification of tumours of the central nervous system.
- Isocitrate dehydrogenase-1 mutations: a fundamentally new understanding of diffuse glioma?
- Correlations between molecular profile and radiologic pattern in oligodendroglial tumors
Cited by
- Anatomical specificity of vascular endothelial growth factor expression in glioblastomas: a voxel-based mapping analysis
- Identifying the Association of Contrast Enhancement with Vascular Endothelia Growth Factor Expression in Anaplastic Gliomas: A Volumetric Magnetic Resonance Imaging Analysis
- Association between molecular alterations and tumor location and MRI characteristics in anaplastic gliomas
- Genomic predictors of patterns of progression in glioblastoma and possible influences on radiation field design
- Patterns of Tumor Contrast Enhancement Predict the Prognosis of Anaplastic Gliomas with IDH1 Mutation
- TERT promoter mutated WHO grades II and III gliomas are located preferentially in the frontal lobe and avoid the midline.
- Imaging Markers of Isocitrate Dehydrogenase-1 Mutations in Gliomas.
- IDH mutations may not preclude distant, trans-tentorial spread in gliomas: a case report and review of the literature
- Radiological features combined with IDH1 status for predicting the survival outcome of glioblastoma patients.
- Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas
- Impact of gross total resection in patients with WHO grade III glioma harboring the IDH 1/2 mutation without the 1p/19q co-deletion
- [Clinical, immunohistochemical, and molecular genetic prognostic factors in adult patients with glioblastoma].
- Frontal glioblastoma multiforme may be biologically distinct from non-frontal and multilobar tumors.
- IDH1 mutation may not be prognostically favorable in glioblastoma when controlled for tumor location: A case-control study.
- Association of The IDH1 C.395G>A (R132H) Mutation with Histological Type in Malay Brain Tumors
- Genetically Defined Oligodendroglioma Is Characterized by Indistinct Tumor Borders at MRI
- IDH mutation assessment of glioma using texture features of multimodal MR images
- Predicting IDH mutation status in grade-II gliomas using amide proton transfer-weighted (APTw) MRI
- Imaging Correlates of Adult Glioma Genotypes.
- T2–FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project
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