Identification of Signal Peptide Peptidase, a Presenilin-Type Aspartic Protease

Keywords

Proteolysis, Signal peptide, Signal peptidase, Biochemistry, Proteases

References

• Intramembrane proteolysis by presenilinsHarald Steiner, Christian Haass — 2000
• Microtechnology: Laying it on thickSarah Tomlin — 1999
• Presenilins, processing of beta-amyloid precursor protein, and notch signaling.Yee-Ming Chan, Yuh Nung Jan — 1999
• Signal sequences: more than just greasy peptides.Bruno Martoglio, Bernhard Dobberstein — 1998
• Translating cell biology into therapeutic advances in Alzheimer's diseaseDennis J. Selkoe — 1999
• Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.Jeffrey R. Lee, Siniša Urban, Clare F. Garvey — 2001
• Evaluation of methods for the prediction of membrane spanning regionsSteffen Möller, Michael D. R. Croning, Rolf Apweiler — 2001
• Release of Signal Peptide Fragments into the Cytosol Requires Cleavage in the Transmembrane Region by a Protease Activity That Is Specifically Blocked by a Novel Cysteine Protease Inhibitor*Andreas Weihofen, Marius K. Lemberg, Hidde L. Ploegh — 2000
• Regulated intramembrane proteolysis takes another twist.Stacey S. Huppert, Raphael Kopan — 2001
• Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.Kyosuke Haze, Hiderou Yoshida, Hideki Yanagi — 1999
• Intramembrane Proteolysis of Signal Peptides: An Essential Step in the Generation of HLA-E Epitopes1Marius K. Lemberg, Felicity A. Bland, Andreas Weihofen — 2001
• γ-Secretase: never more enigmaticSangram S. Sisodia, Wim Annaert, Seong‐Hun Kim — 2001
• Regulated Intramembrane Proteolysis : Review A Control Mechanism Conserved from Bacteria to HumansMichael S. Brown, Jin Ye, R. B. Rawson — 2000

Cited by

• Aging, Amyloid, and Alzheimer's Disease: A Perspective in Honor of Carl CotmanDennis J. Selkoe — 2003
• Functional Characterization of the Presenilin Homologue SPE-4Aya Yamasaki-Meythaler — 2006
• Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.Akiko Ogawa Kawata — 2003
• On the mechanism of SPP‐catalysed intramembrane proteolysis; conformational control of peptide bond hydrolysis in the plane of the membraneMarius K. Lemberg, Bruno Martoglio — 2004
• SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 productionВ.А. Гордиенко, Л.Н. Захаров, В.И. Ильичев — 2006
• Assembly, Trafficking and Function of γ-SecretaseAdam Simpson — 2006
• Presenilins: members of the gamma-secretase quartets, but part-time soloists too.Tomoko Wakabayashi, Bart De Strooper — 2008
• Chemical probes for profiling fatty acid-associated proteins in living cells.Блягоз Заурбий Зулькаринович — 2008
• CHARACTERIZATION OF FACTORS THAT IMPACT APOLIPOPROTEIN BSECRETION AND ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATIONSarah R. Grubb — 2013
• The Role of Adams in Notch SignalingArjan J. Groot, Marc Vooijs — 2012
• Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling.Natalie Landman, Tae‐Wan Kim — 2004
• Assemble and Interact: Pleiotropic Functions of the HCV Core ProteinStephen J. Polyak, Kevin Klein, Ikuo Shoji — 2006
• Protein aggregation as a cause for disease.Thomas Scheibel, Johannes Büchner — 2006
• The generation of the amyloid precursor protein intracellular domainC. Duggan — 2005
• Studies on membrane-bound peptidases and a sugar transporter in the hyperthermophilic archaeon Thermococcus kodakaraensisR. Matsumi — 2008
• HCV NS4B: From Obscurity to Central StageElla H. Sklan, Jeffrey S. Glenn — 2006
• Human dendritic cells and hepatitis C VirusAbdolamir Landi — 2009
• Processing of the amyloid precursor protein and its paralogues amyloid precursor-like proteins 1 and 2Linda Adlerz — 2007
• The fate of endoplasmic reticulum-targeted proteins in the face of proteasome failureFranziska Hofer — 2015
• Detection of protease activity in cells and animals.Martijn Verdoes, Steven H. L. Verhelst — 2016

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