The FEN‐1 family of structure‐specific nucleases in eukaryotic dna replication, recombination and repair
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Summary
The crystal structures of two enzymes in the F EN‐1 nuclease family have been solved and they provide a structural basis for the interesting steric requirements of FEN‐1 substrates.
- Type
- review
- Published
- 1997-03-01
- Cited by
- 449
- References
- 38
- OpenAlex
- https://openalex.org/W2033676950
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37295581
Keywords
Biology, DNA polymerase, Eukaryotic DNA replication, DNA replication, Okazaki fragments
References
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- The characterization of a mammalian DNA structure‐specific endonuclease.
- Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
- A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
- Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.
- Coding end sequence can markedly affect the initiation of V(D)J recombination.
- Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases.
- Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen (*)
- Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins.
- Structure-specific Nuclease Activity in Yeast Nucleotide Excision Repair Protein Rad2 (*)
Cited by
- Ribonucleases H of the budding yeast, Saccharomyces cerevisiae.
- Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair*
- Triplet repeats form secondary structures that escape DNA repair in yeast.
- The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities.
- Flap endonuclease 1: a central component of DNA metabolism.
- Saccharomyces cerevisiae RAD27 complements its Escherichia coli homolog in damage repair but not mutation avoidance.
- Human 3-methyladenine-DNA glycosylase: effect of sequence context on excision, association with PCNA, and stimulation by AP endonuclease.
- Repair and tolerance of DNA damage in higher plants
- Did an early version of the eukaryal replisome enable the emergence of chromatin?
- Interaction of Flap Endonuclease-1 and Replication Protein A with Photoreactive Intermediates of DNA Repair
- Incision Coordination in Nucleotide Excision Repair
- Cancer Specific Proliferating Cell Nuclear Antigen as a Novel Diagnostic Marker for the Detection of Breast Cancer
- Pruning DNA: structure-specific endonucleases (XPF/Rad1/Mus81).
- Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control.
- Maintenance génomique chez l'Archaea hyperthermophile Pyrococcus abyssi : découverte de nouvelles interactions physiques et caractérisation fonctionnelle
- The Eukaryotic Replication Complex and Its Affinity Modification Analysis
- Physiological aspects of UV-excitation of DNA.
- OsSEND-1: a new RAD2 nuclease family member in higher plants
- Characterising the role of murine gammaherpesvirus-68 host shutoff protein in mediating cellular mRNA degradation
- Checkpoint Regulation of Replication Forks in Response to DNA Damage: A Dissertation
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