Prediction and functional analysis of native disorder in proteins from the three kingdoms of life.
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Summary
An automatic method for recognizing natively disordered regions from amino acid sequence is described and benchmarked against predictors that were assessed at the latest critical assessment of techniques for protein structure prediction (CASP) experiment and represents a statistically significant improvement on the methods evaluated on the same targets at CASP.
- Type
- article
- Published
- 2004-03-26
- Cited by
- 2,017
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W2030776726
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14438715
Keywords
Gene ontology, CASP, Computational biology, Proteome, Biology
References
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- Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA
Cited by
- Structural Insights into the Shroom-Rock Interaction and the Regulation of the Actomyosin Cytoskeleton
- Bioinformatic analysis of protein structure–function relationships: case study of leukocyte elastase (ELA2) missense mutations
- Transition of Tau Protein from Disordered to Misordered in Alzheimer’s Disease
- Mapping protective epitopes in the tick and mosquito subolesin ortholog proteins.
- ChePep Controls Helicobacter pylori Infection of the Gastric Glands and Chemotaxis in the Epsilonproteobacteria
- Predicting protein-ATP binding sites from primary sequence through fusing bi-profile sampling of multi-view features
- Roles for intrinsic disorder and fuzziness in generating context-specific function in Ultrabithorax, a Hox transcription factor.
- Disordered Binding Regions and Linear Motifs—Bridging the Gap between Two Models of Molecular Recognition
- DNdisorder: predicting protein disorder using boosting and deep networks
- FFPred 2.0: Improved Homology-Independent Prediction of Gene Ontology Terms for Eukaryotic Protein Sequences
- The cytoplasmic domain of the T-cell receptor zeta subunit does not form disordered dimers
- N-terminal protein tails act as aggregation protective entropic bristles: the SUMO case.
- DISOPRED3: precise disordered region predictions with annotated protein-binding activity
- A feature analysis of lower solubility proteins in three eukaryotic systems.
- Subgroup-specific intrinsic disorder profiles of arabidopsis NAC transcription factors: Identification of functional hotspots
- Hydrodynamic Radii of Intrinsically Disordered Proteins Determined from Experimental Polyproline II Propensities
- The intrinsic disorder alphabet. III. Dual personality of serine
- Characterization of phosphate transporter(s) and understanding their role in Leishmania donovani parasite
- Structure, Dynamics, and Evolution of the Intrinsically Disordered p53 Transactivation Domain
- Molecular characterisation of the SAND protein family: a study based on comparative genomics, structural bioinformatics and phylogeny.
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