Pathogenesis of cutaneous lesions in acute meningococcemia in humans: light, immunofluorescent, and electron microscopic studies of skin biopsy specimens.
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Summary
The findings suggest that the cutaneous lesions of meningococcemia fulfill most of the gross and histologic criteria of the local Shwartzman reaction, but that immunological factors probably contribute to pathogenesis.
- Type
- article
- Published
- 1976-05-01
- Cited by
- 85
- References
- 11
- OpenAlex
- https://openalex.org/W2030295614
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38255905
Keywords
Pathogenesis, Pathology, Electron microscope, Necrosis, Neisseria meningitidis
References
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- An appraisal of fulminant meningococcemia with reference to the Shartzman phenomenon.
- Fatal intravascular consumption coagulopathy in meningococcal sepsis.
- The cutaneous lesions in acute meningococcemia; a clinical and pathologic study.
- Group-specific polysaccharide antigen and humoral antibody response in disease due to Neisseria meningitidis.
- An electron microscope study of endotoxin shock in rhesus monkeys.
- Electron microscopy of muscle biopsies in two cases of meningococcemia.
- Meningococcal meningitis: past and present concepts.
- STUDIES ON THE MECHANISM OF THE SHWARTZMAN PHENOMENON
Cited by
- Purpura fulminans in meningococcemia: association with acquired deficiencies of proteins C and S.
- Skin loss in meningococcal septicaemia.
- High‐level endothelial E‐selectin (CD62E) cell adhesion molecule expression by a lipopolysaccharide‐deficient strain of Neisseria meningitidis despite poor activation of NF‐κB transcription factor
- Adrenal, cutaneous and myocardial lesions in fulminating endotoxinemia (Waterhouse-Friderichsen syndrome).
- Rare complications in a case of generalized meningococcal disease: Immunologic reaction versus bacterial metastasis
- Isquemia digital del miembro inferior: reversión mediante bloque simpático
- Pathology of the Cutaneous Vasculitides: A Comprehensive Review
- 3 – Infectious Diseases of the Skin
- Outer membrane vesicles from Neisseria meningitidis
- Acute bacterial septic vasculopathy
- Vasculitides associated with infections, immunization, and antimicrobial drugs.
- Pathogenesis and diagnosis of human meningococcal disease using immunohistochemical and PCR assays.
- Skin necrosis secondary to meningococcal septicaemia in an adult.
- Cutaneous Vasculitis Update: Small Vessel Neutrophilic Vasculitis Syndromes
- Use of topically applied nitroglycerin in the treatment of purpura fulminans.
- Cutaneous and soft-tissue manifestations of sepsis due to gram-negative enteric bacilli.
- Postinfectious purpura fulminans caused by an autoantibody directed against protein S.
- Purpura in infants and children.
- Purpura fulminans méningococcique : Particularités physiopathologiques
- Infection with Borrelia recurrentis: pathogenesis of fever and petechiae.
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