Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

Keywords

Focal adhesion, PTK2, Cell biology, Extracellular matrix, Tyrosine phosphorylation

References

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Cited by

• The role and regulation of PAK isoforms in cancer cell migrationMichael D. Bright — 2008
• The Related Adhesion Focal Tyrosine Kinase Forms a Complex with Paxillin in Hematopoietic Cells*Ruth López Alonso, Javier Martínez Bajo — 1996
• The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesionsBalbina Martínez Caviró — 1997
• Integrin signaling: specificity and control of cell survival and cell cycle progression.Andrew M. Michael — 1997
• Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells.Nur Inayah — 1999
• FAK integrates growth-factor and integrin signals to promote cell migrationMaría Pilar Celma Valero — 2000
• Focal Adhesion Kinase Activates Stat1 in Integrin-mediated Cell Migration and Adhesion*Bing Xie, Jihe Zhao, Motoo Kitagawa — 2001
• Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity.Paul Timpson, Gareth E. Jones, Margaret C. Frame — 2001
• Roles for zebrafish focal adhesion kinase in notochord and somite morphogenesis.Clarissa A. Henry, Bryan D. Crawford, Yi‐Lin Yan — 2001
• The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin SignalingSmitha Sundaram, B.G. Eldridge — 2002
• Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: which side to target?John F. Coverdale, Fernando Santos Fontenla — 2002
• Tumour-cell invasion and migration: diversity and escape mechanismsI. S. Shikin — 2003
• FAK induces expression of Prx1 to promote tenascin-C–dependent fibroblast migrationJulio Antonio García López, Antonio María Ávila Álvarez, Miguel Ángel Díaz Mier — 2003
• Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression.David G. Schultz — 2003
• Focal adhesion kinase (FAK) expression and phosphorylation in sea urchin embryos.Н.М. Бирюков, Виктор Михайлович Сергеев — 2004
• Weak Expression of Focal Adhesion Kinase (pp125FAK) in Patients with Cervical Cancer Is Associated with Poor Disease OutcomeBoris Gabriel, Axel zur Hausen, Elmar Stickeler — 2006
• Tissue inhibitor of metalloproteinases 3 regulates extracellular matrix--cell signaling during bronchiole branching morphogenesis.Lance H. Wuellner — 2006
• CAP interacts with cytoskeletal proteins and regulates adhesion‐mediated ERK activation and motility史朗 三輪 — 2006
• Signaling mechanisms utilized by antigen receptors and integrins: common intermediates, different outcomes?Alicia Namesny Vallespir — 2007
• Erk1/2 MAPK and caldesmon differentially regulate podosome dynamics in A7r5 vascular smooth muscle cells.Taebum Lee — 2007

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• Microinjection of protein tyrosine phosphatases into fibroblasts disrupts focal adhesions and stress fibers.Galen B. Schneider, Andrew Gilmore, Lewis H. Romer — 1998