Sickle cell anemia a molecular disease.
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Summary
The erythrocytes of certain individuals possess the capacity to undergo reversible changes in shape in response to changes in the partial pressure of oxygen, and these cells change their forms from the normal biconcave disk to crescent, holly wreath, and other forms.
- Type
- article
- Published
- 1949-11-25
- Cited by
- 1,988
- References
- 12
- OpenAlex
- https://openalex.org/W2027816595
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31674765
Keywords
Disease, Anemia, Sickle cell anemia, Cell, Medicine
References
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- Spectrophotometric studies; the crystallographic and optical properties of the hemoglobin of man in comparison with those of other species.
- THE TITRATION CURVES OF OXYGENATED AND REDUCED HEMOGLOBIN
- RED CELL CYTOCHEMISTRY AND ARCHITECTURE
- The Inheritance of Sickle Cell Anemia.
- AN ELECTROPHORETIC STUDY OF IMMUNE SERA AND PURIFIED ANTIBODY PREPARATIONS
- The Effects of Changes in Quantity, Combination, and Position of Genes.
- An electrophoresis apparatus using parabolic mirrors.
- THE INFLUENCE OF pH ON THE MOBILITY AND DIFFUSION OF OVALBUMIN
- THE NATURE OF THE FORCES BETWEEN ANTIGEN AND ANTIBODY AND OF THE PRECIPITATION REACTION
- On the electrophoretic pattern of red blood cell proteins.
- Textbook of Pathology
Cited by
- Hemoglobin interaction in sickle cell fibers. I: Theoretical approaches to the molecular contacts.
- Relations between oxygen saturation and aggregation of sickle-cell hemoglobin.
- Sickle cell disease: implications for nursing care.
- Increased metabolic heat production by erythrocytes in sickle-cell disease.
- Clinically important variants of human hemoglobin.
- A new intellectual framework for psychiatry.
- Vitreous hemorrhage and retinopathy associated with sickle-cell disease.
- OCULAR COMPLICATIONS IN SICKLE-CELL HAEMOGLOBIN C DISEASE*
- The Human Genome Diversity Project: past, present and future
- Recombinant sickle hemoglobin containing a lysine substitution at Asp-85(alpha): expression in yeast, functional properties, and participation in gel formation.
- Role of Alu Element in Detecting Population Diversity
- Iron Metabolism and Iron Chelation in Sickle Cell Disease
- Notes of a protein crystallographer: the molecular structure of evolutionary theory.
- Acquisizioni moderne in tema di emoglobinopatie
- Sickle cell disease: new insights into pathophysiology and treatment.
- Perspective: Reaches of chemical physics in biology.
- Out with the bad and in with the good; red cell exchange, white cell reduction, and platelet reduction
- Crystal Structure of Carbonmonoxy Sickle Hemoglobin in R-state Conformation
- Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
- Sickle cell disease--the American saga.
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