Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma.

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Summary

Findings indicate an important role of Rsf-1 amplification in ovarian cancer, which had a significantly shorter overall survival than those without and stimulated cell proliferation and transform nonneoplastic cells by conferring serum-independent and anchorage-independent growth.

Type
article
Published
2005-09-27
Cited by
139
References
30
Access
Open access

Keywords

Amplicon, Gene duplication, Biology, Gene, Ovarian cancer

References

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