Electrostatic effects in DNA triple helices.
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Summary
To investigate the extent of the local and global electrostatic effects further, two families of oligonucleotides have been synthesized and share as a common design feature that they all fold sequentially into isosterical intramolecular triple helices by way of hairpin intermediates.
- Type
- article
- Published
- 1994-11-15
- Cited by
- 82
- References
- 73
- OpenAlex
- https://openalex.org/W2026951046
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41475648
Keywords
Citation, Computer science, Social media, Icon, Information retrieval
References
- COMPLEX FORMATION BETWEEN POLYCYTIDYLIC ACID AND GUANINE OLIGONUCLEOTIDES.
- Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif.
- Triple helix formation by oligopurine-oligopyrimidine DNA fragments. Electrophoretic and thermodynamic behavior.
- Structure and stability of X.G.C mismatches in the third strand of intramolecular triplexes.
- Formation of two- and three-Stranded Helical Molecules by Polyinosinic Acid and Polyadenylic Acid
- Triple-Stranded Polynucleotide Helix Containing Only Purine Bases
- Na+ effects on transitions of DNA and polynucleotides of variable linear charge density
- Comparative circular dichroism and fluorescence studies of oligodeoxyribonucleotide and oligodeoxyribonucleoside methylphosphonate pyrimidine strands in duplex and triplex formation.
- Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatches.
- Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif.
- Structures for the polynucleotide complexes poly(dA) with poly (dT) and poly(dT) with poly(dA) with poly (dT).
- Formation of the triple-stranded polynucleotide helix, poly(A.A.U).
- Triple-helix formation by oligodeoxynucleotides containing the carbocyclic analogs of thymidine and 5-methyl-2'-deoxycytidine
- Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.
- Sequence-specific alkylation of double-helical DNA by oligonucleotide-directed triple-helix formation
- Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature.
- Physical studies of DNA premelting equilibria in duplexes with and without homo dA.dT tracts: correlations with DNA bending.
- Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites.
- Stabilities of double- and triple-strand helical nucleic acids.
- CD of homopolymer DNA-RNA hybrid duplexes and triplexes containing A-T or A-U base pairs.
Cited by
- Fluorescent probe for proton-coupled DNA folding revealing slow exchange of i-motif and duplex structures.
- Triplex forming oligonucleotides--tool for gene targeting.
- Pyrimidine Oligodeoxyxylonucleotides Form Triplexes with Purine DNA in Neutral Medium
- Modeling Low-Barrier Hydrogen Bonds and Solution Effects
- The structures and proton transfer barriers in proton-bound homodimers of aromatic molecular bases : Implication of zero-point energies for the proton-transfer reaction
- Synthesis of 5-[3-(2-aminopyrimidin-4-yl)aminopropyn-1-yl]uracil derivative that recognizes Ade-Thy base pairs in double-stranded DNA.
- Counterion association with native and denatured nucleic acids: an experimental approach.
- In Silico Search of DNA Drugs Targeting Oncogenes
- Drug Binding, Order-Order and Order-Disorder Transitions in DNA Triple Helices
- Triple helix formation at (AT)n adjacent to an oligopurine tract.
- Stabilisation of non-canonical structures of nucleic acids by metal ions and small molecules
- Monitoring denaturation behaviour and comparative stability of DNA triple helices using oligonucleotide-gold nanoparticle conjugates.
- Thermodynamics of oligonucleotide triple helices
- Thermodynamic Basis For Engineering High Affinity, High Specificity Binding-Induced DNA Clamp Nanoswitches
- Formation of stable DNA triplexes.
- Triplex formation at physiological pH by 5-Me-dC-N4-(spermine) [X] oligodeoxynucleotides: non protonation of N3 in X of X*G:C triad and effect of base mismatch/ionic strength on triplex stabilities.
- Theoretical study of the ionic hydrogen bond in the isolated proton-bound dimer of cytosine
- Protonation of deoxycytidine residues in dC4 tetraloops: UV spectrophotometric study of dC10 and d(A14C4T14).
- Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.
- A four-way junction with triple-helical arms: design, characterization, and stability.
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