Aspirin for the Primary Prevention of Cardiovascular Events in Women and Men: A Sex-Specific Meta-Analysis of Randomized Controlled Trials
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Summary
For women and men, aspirin therapy reduced the risk of a composite of cardiovascular events due to its effect on reducing the risk of ischemic stroke in women and MI in men and increased the risk of bleeding to a similar degree among women and men.
- Type
- review
- Published
- 2006-01-18
- Cited by
- 4,031
- References
- 30
- OpenAlex
- https://openalex.org/W2025039880
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11586477
Keywords
Medicine, Aspirin, Stroke (engine), Myocardial infarction, Odds ratio
References
- Aspirin for the Primary Prevention of Cardiovascular Events: Recommendation and Rationale
- Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women
- Prevention of coronary heart disease in clinical practice: recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention.
- Review: aspirin was effective for primary prevention of stroke in women and MI in men but increased major bleeding
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- Randomised trial of prophylactic daily aspirin in British male doctors
- Profile and prevalence of aspirin resistance in patients with cardiovascular disease.
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- Clinical pharmacology of platelet cyclooxygenase inhibition.
- Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials.
- Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
- Selecting and Appraising Studies for a Systematic Review
- Routine vs selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials.
- Differential inhibition by aspirin of vascular and platelet prostaglandin synthesis in atherosclerotic patients.
- Anti-Platelet Effects of 100 mg Alternate Day Oral Aspirin: A Randomized, Double-Blind, Placebo-Controlled Trial of Regular and Enteric Coated Formulations in Men and Women
- Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin.
- Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects.
- Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
- AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association Science Advisory and Coordinating Committee.
- An update on aspirin in the primary prevention of cardiovascular disease.
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- Prevention of recurrent ischemic stroke.
- Aspirin for primary prevention of cardiovascular events in diabetes: still an open question.
- Hyperthermic intraperitoneal chemotherapy in the management of ovarian cancer: A critical need for an evidence-based evaluation.
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- Fruit and vegetable intakes and subsequent changes in body weight in European populations: results from the project on Diet, Obesity, and Genes (DiOGenes).
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