Profilin interacts with the Gly-Pro-Pro-Pro-Pro-Pro sequences of vasodilator-stimulated phosphoprotein (VASP): implications for actin-based Listeria motility.
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Summary
It is reported that fluorescence titration showed that GP5GP5 GP5 peptide binds to profilin, and the peptide weakly inhibits exchange of actin-bound nucleotide in the absence or presence ofprofilin.
- Type
- article
- Published
- 1997-07-08
- Cited by
- 126
- References
- 0
- OpenAlex
- https://openalex.org/W2024171558
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46208157
Keywords
Profilin, Phosphoprotein, Actin, Actin-binding protein, Chemistry
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Cited by
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- Protein kinase C isozyme-specific phosphorylation of profilin.
- Listeria and Shigella actin-based motility in host cells.
- ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor.
- Energetics of nucleotide hydrolysis in polymer assembly/disassembly: the cases of actin and tubulin.
- Actin-binding proteins: an overview.
- Changes of vasodilator‐stimulated phosphoprotein (VASP) and its phosphorylation in endothelial cells exposed to laminar flow
- VASP and Profilin-1 Interaction in Cell Migration
- Listeria monocytogenes : pathogenesis and host response
- The Dual Function of the Chlamydia pneumoniae Cpn0572 Protein in Modulating the Host Actin Cytoskeleton
- A novel inhibitory pathway linking profilin-1 and breast cancer cell motility
- The Vasodilator-Stimulated Phosphoprotein Is Regulated by Cyclic GMP-Dependent Protein Kinase During Neutrophil Spreading1
- The palladin/myotilin/myopalladin family of actin-associated scaffolds.
- Regulating Actin Dynamics at Membranes: A Focus on Dynamin
- Functional Analysis of a Rickettsial OmpA Homology Domain of Shigella flexneri IcsA
- Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.
- Accumulation of profilin II at the surface of Listeria is concomitant with the onset of motility and correlates with bacterial speed.
- Gelsolin, a Protein That Caps the Barbed Ends and Severs Actin Filaments, Enhances the Actin-Based Motility ofListeria monocytogenes in Host Cells
- Pathogenic microbes manipulate cofilin activity to subvert actin cytoskeleton
- High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP.
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