Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors
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Summary
Preursors of cytotoxic cells thus have the same high frequency of cells reactive to alloantigens of the major histocompatibility complex as found among proliferating cells in graft- vs-host reactions and mixed lymphocyte interactions.
- Type
- article
- Published
- 1977-03-01
- Cited by
- 379
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W2023201913
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18299653
Keywords
CTL*, Cytotoxic T cell, Antigen, Biology, Histocompatibility
References
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- Specificity of Cell‐Mediated Lympholysis for Public and Private H‐2 Determinants
- QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS
- Separation of suppressor and killer T cells by surface phenotype
- H‐2 and non‐H‐2 determinants in the genetic control of cell‐mediated lympholysis
- Cell kinetic studies in mixed leukocyte cultures: an in vitro model of homograft reactivity.
- Cell Mediated Immunity: Separation of Cells Involved in Recognitive and Destructive Phases
- Separation of helper T cells from suppressor T cells expressing different Ly components. II. Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses
- Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes
- H‐2 antigen‐specific cytotoxic T cells induced by concanavalin A: estimation of their relative frequency
- The requirement for DNA synthesis and gene expression in the generation of cytotoxicity in vitro
- Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen
- THE RELATIONSHIP OF CELL DIVISION TO THE GENERATION OF CYTOTOXIC ACTIVITY IN MIXED LYMPHOCYTE CULTURE
- An estimation of the frequency of precursor cells which generate cytotoxic lymphocytes
- Histocompatibility antigen-activated cytotoxic T lymphocytes. I. Estimates of the absolute frequency of killer cells generated in vitro
- Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses
- EFFECT OF M‐LOCUS DEPENDENT T‐CELL PROLIFERATION UPON THE INDUCTION OF ANTI H‐2 CYTOTOXIC T EFFECTOR CELLS
- Early cellular events in a systemic graft-vs.-host reaction. I. The migration of responding and nonresponding donor lymphocytes
Cited by
- Cellular and molecular events in the delayed-onset hypersensitivities.
- The decay of memory of cell-mediated cytotoxicity after primary sensitization in vivo against a tumor allograft.
- Clonal analysis of the effect of iron on human cytotoxic and proliferating T lymphocytes
- The molecular basis of alloreactivity in antigen-specific, major histocompatibility complex-restricted T cell clones.
- The MHC reactivity of the T cell repertoire prior to positive and negative selection.
- T‐Cell Allorecognition and Transplant Rejection: A Summary and Update
- Fine specificity of auto- and alloreactive cytotoxic T-lymphocytes: heteroclitic cross-reactions between mutant and original H-2 antigens.
- HIV induced AIDS and related cancers: chronic immune activation and future therapeutic strategies.
- On network theory and H-2 restriction.
- The Humanized Mouse Model: The Study of the Human Alloimmune Response: A Dissertation
- Cytotoxic T-memory cells in virus infection and the specificity of helper T cells.
- IFN-α/β Induction by dsRNA and Toll-Like Receptors Shortens Allograft Survival Induced by Costimulation Blockade: A Dissertation
- Autoimmune Diabetes and Transplantation Tolerance Induced by Costimulation Blockade in NOD Mice: a Dissertation
- The role of the major histocompatibility gene complex in murine cytotoxic T cell responses.
- Prevention of marrow graft rejection without induction of graft-versus-host disease by a cytotoxic T-cell clone that recognizes recipient alloantigens.
- Contribution à l’analyse des mécanismes impliqués dans le maintien de la tolérance induite par transfusion spécifique de sang du donneur
- The Human T-Cell Receptor Repertoire and Transplantation
- The Immune Response to Alloantigens
- Platelet-Derived Growth Factor and Proinflammatory Cytokines in Cardiac Allograft Arteriosclerosis
- Role of H-2 antigens in the host response to methylcholanthrene-induced tumors
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