Complete development in vitro of the pre-implantation stages of the mouse in a simple chemically defined medium.

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Summary

A simple chemically defined medium is described in which the eggs ofcertain hybrid mice develop from the 1-cell stage to the blastocyst completely in vitro, which is capable of implantation and thus overcome the final barrier which prevented complete development in vitro of the pre-implantation stages of a mammal independent of the female genital tract.

Type
article
Published
1968-11-01
Cited by
469
References
8
Access
Open access

Keywords

Embryo, Zygote, In vitro, Cleave, Andrology

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