Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.
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Summary
It is demonstrated that most allergen-specific helper T cells in atopic individuals are able to produce high amounts of IL-4 (and IL-5), but no IFN-gamma, which may explain why allergens induce production of IgE antibodies and increase eosinophils.
- Type
- article
- Published
- 1991-05-15
- Cited by
- 658
- References
- 1
- Access
- Open access
- OpenAlex
- https://openalex.org/W2020977425
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13337146
Keywords
Immunology, Antigen, Immunoglobulin E, Allergen, Toxoid
References
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