Clinical trials with thiazolidinediones in subjects with Type 2 diabetes--is pioglitazone any different from rosiglitazone?
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Summary
Unless the thiazolidinediones are shown to improve cardiovascular or other outcomes (e.g., renal) in the next few years, their continued use in T2DM should be questioned.
- Type
- review
- Published
- 2008-01-28
- Cited by
- 16
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W2020625666
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22627524
Keywords
Pioglitazone, Rosiglitazone, Medicine, Internal medicine, Endocrinology
References
- Pioglitazone and Rosiglitazone Have Different Effects on Serum Lipoprotein Particle Concentrations and Sizes in Patients With Type 2 Diabetes and Dyslipidemia
- Effects of Pioglitazone on Endothelial Function, Insulin Sensitivity, and Glucose Control in Subjects With Coronary Artery Disease and New-Onset Type 2 Diabetes
- Rosiglitazone Monotherapy Is Effective in Patients with Type 2 Diabetes
- Effects of Pioglitazone on Endothelial Function, Insulin Sensitivity, and Glucose Control in Subjects With Coronary Artery Disease and New-Onset Type 2 Diabetes
- Rosiglitazone Monotherapy Is Effective in Patients with Type 2 Diabetes
- White blood cell count and cardiovascular disease. Insights from the Framingham Study
Cited by
- Evaluation of the efficacy and tolerability of miglitol in Chinese patients with type 2 diabetes mellitus inadequately controlled by diet and sulfonylureas
- Dapagliflozin – do we need it registered for type 2 diabetes?
- Rosiglitazone via PPARγ-dependent suppression of oxidative stress attenuates endothelial dysfunction in rats fed homocysteine thiolactone
- The Effects of Thiazolidinediones on Metabolic Complications and Lipodystrophy in HIV-Infected Patients
- Factors affecting proteoglycan synthesis and structure that modify the interaction with lipoproteins
- Optimized mixture of hops rho iso-alpha acids-rich extract and acacia proanthocyanidins-rich extract reduces insulin resistance in 3T3-L1 adipocytes and improves glucose and insulin control in db/db mice
- Effect of Pioglitazone, Quercetin, and Hydroxy Citric Acid on the Lipid Profile and Lipoproteins in Experimentally Induced Non-alcoholic Steatohepatitis (NASH)
- Pioglitazone: a valuable component of combination therapy for type 2 diabetes mellitus
- Transient Increase in HDL‐Cholesterol During Weight Gain by Hyperalimentation in Healthy Subjects
- SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism
- Comment and response to: dapagliflozin – do we need it registered for type 2 diabetes?
- Is the risk of cardiovascular disease altered with anti-inflammatory therapies? Insights from rheumatoid arthritis
- Treatment of Dyslipidemias to Prevent Cardiovascular Disease in Patients with Type 2 Diabetes
- Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies
- Pioglitazone/metformin adduct regulates insulin secretion and inhibits high glucose‐induced apoptosis via p21‐p53‐MDM2 signaling in INS‐1 cells
- Efficacy and Safety of Pioglitazone/Metformin Fixed-Dose Combination Versus Uptitrated Metformin in Patients with Type 2 Diabetes without Adequate Glycemic Control: A Randomized Clinical Trial
- Red clover extract
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