Patterns of Aneusomy for Three Chromosomes in Individual Cells from Breast Cancer Tumors
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Summary
Certain patterns of aneusomy in individual cells involving chromosomes 1, 8 and 17 are indicative of malignancy in individual breast tumor cells and may be useful for determining malignancies of rare epithelial cells in the blood of breast cancer patients.
- Type
- article
- Published
- 2002-10-01
- Cited by
- 42
- References
- 38
- OpenAlex
- https://openalex.org/W2020377715
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22710791
Keywords
Malignancy, Breast cancer, Biology, Breast carcinoma, Pathology
References
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- Incidence of chromosomes 1 and 17 aneusomy in breast cancer and adjacent tissue: an interphase cytogenetic study.
- Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas.
- Interphase cytogenetics in mammographically detected breast lesions.
- Detection of chromosomal aneusomy by fluorescence in situ hybridization in fine‐needle aspirates from breast tumors
- Interphase fluorescence in situ hybridization improves the detection of malignant cells in effusions from breast cancer patients.
- Genetic alterations of chromosome 17 in human breast carcinoma studied by fluorescence in situ hybridization and molecular DNA techniques.
- Identification and characterization of circulating prostate carcinoma cells
- Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH.
- Chromosome abnormalities in breast fibroadenomas.
- Stage I and stage II infiltrating ductal carcinoma of the breast analyzed for chromosome 8 copy number using fluorescent in situ hybridization.
- Clinicopathologic analysis of breast carcinoma with chromosomal aneusomy detected by fluorescence in situ hybridization
- Genetic alterations in breast cancer
- Interphase cytogenetics reveals a high incidence of aneuploidy and intra-tumour heterogeneity in breast cancer.
- Aneuploidy of chromosome 8 as detected by interphase fluorescence in situ hybridization is a recurrent finding in primary and metastatic breast cancer
- Analysis of numerical aberrations in specific chromosomes by fluorescent in situ hybridization as a diagnostic tool in breast cancer
- Somatic genetic changes in human breast cancer.
- Interphase cytogenetics: Analysis of numerical chromosome aberrations in isolated cells
- Advantages and limitations of using fluorescence in situ hybridization for the detection of aneuploidy in interphase human cells.
Cited by
- Malignant characteristics of circulating tumor cells and corresponding primary tumor in a patient with esophageal squamous cell carcinoma before and after surgery
- Vergleich einer neuen RT-PCR-basierten Methode zum Nachweis disseminierter Tumorzellen im Knochenmark von Mammakarzinompatientinnen mit Immunzytochemie
- Prediction of Axillary Lymph Node Status of Breast Cancer Patients by Tumorbiological Factors of the Primary Tumor
- Ductal approaches to assessment and management of women at high risk for developing breast cancer
- Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant.
- High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome
- Determinación de anomalías cromosómicas y secuencias de ADN amplificadas en cáncer de mama
- [Detection of disseminated tumor cells in the bone marrow of breast cancer patients with a new molecular method].
- c-myc, not her-2/neu, can predict the prognosis of breast cancer patients: how novel, how accurate, and how significant?
- Human BRCA1-Associated Breast Cancer: No Increase in Numerical Chromosomal Instability Compared to Sporadic Tumors
- Nanotopographic Biomaterials for Isolation of Circulating Tumor Cells
- Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapies
- Slit Protein-mediated Inhibition of CXCR4-induced Chemotactic and Chemoinvasive Signaling Pathways in Breast Cancer Cells*
- Methods for isolating circulating epithelial cells and criteria for their classification as carcinoma cells.
- Breast cancer and aneusomy 17: implications for carcinogenesis and therapeutic response
- Correlation of cytologic findings and chromosomal instability detected by fluorescence in situ hybridization in breast fine-needle aspiration specimens from women at high risk for breast cancer
- uPAR and HER2 Genes Are Usually Co-Amplified in Individual Breast Cancer Cells from Blood and Tissues
- Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
- Changes in the Expression of Many Ets Family Transcription Factors and of Potential Target Genes in Normal Mammary Tissue and Tumors*
- Clinical relevance of circulating CK-19 mRNA-positive cells detected during the adjuvant tamoxifen treatment in patients with early breast cancer.
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