Growth factors and hemostasis: differential effects of GM-CSF and G-CSF on coagulation activation – laboratory and clinical evidence
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Summary
Unlike G-CSF, if given after hyper-ME chemotherapy plus stem cell or bone marrow transplantation, at the dosage used here GM- CSF induced an activation of the coagulation system and was associated with an increased risk of hemostasis associated treatment complications.
- Type
- article
- Published
- 2001-08-01
- Cited by
- 12
- References
- 22
- OpenAlex
- https://openalex.org/W2019832106
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26150752
Keywords
Medicine, Hemostasis, Internal medicine, Hematology, Granulocyte colony-stimulating factor
References
- Neutrophil activation and hemostatic changes in healthy donors receiving granulocyte colony-stimulating factor.
- Effects of granulocyte colony-stimulating factor on the hemostatic system in healthy volunteers.
- Plasminogen activator in granulocyte-macrophage-CSF transgenic mice.
- Granulocyte-colony stimulating factor inhibits TNFα production in a human hepatoma cell line
- In vitro and in vivo activation of endothelial cells by colony-stimulating factors.
- Clinical Toxicity of Cytokines Used As Haemopoietic Growth Factors
- Factors predicting morbidity following hematopoietic stem cell transplantation
- Arterial thrombosis associated with granulocyte-macrophage colony-stimulating factor (GM-CSF) administration in breast cancer patients treated with dose-intensive chemotherapy: a report of two cases.
- Acute arterial thrombosis due to platelet aggregation in a patient receiving granulocyte colony‐stimulating factor
- G-CSF-Induced Mobilization of Peripheral Blood Stem Cells from Healthy Adults for Allogeneic Transplantation
- Subretinal haemorrhage after granulocyte colony-stimulating factor.
- Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony-stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma.
- Analysis of rhG-CSF-effects on platelets by in vitro bleeding test and transcranial Doppler ultrasound examination
- Recombinant human granulocyte and granulocyte–macrophage colony-stimulating factor (G-CSF and GM-CSF) administered following cytotoxic chemotherapy have a similar ability to mobilize peripheral blood stem cells
- Effects of recombinant human granulocyte-macrophage colony-stimulating factor on platelet survival and activation using a nonhuman primate model.
- Granulocyte and granulocyte-macrophage colony-stimulating factors exert differential effects on neutrophil platelet-activating factor generation and release.
- Reduction of plasma fibrinolytic activity following high-dose cyclophosphamide is neutralized in vivo by GM-CSF administration.
- Granulocyte colony-stimulating factor downregulates allogeneic immune responses by posttranscriptional inhibition of tumor necrosis factor-alpha production.
- Granulocyte macrophage colony stimulating factor: high incidence of apheresis catheter thrombosis during peripheral stem cell collection.
- Enhancement of plasminogen activator activity in cultured endothelial cells by granulocyte colony‐stimulating factor
Cited by
- Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiographic safety profile.
- Mobilization of Hematopoietic Stem/Progenitor Cells: General Principles and Molecular Mechanisms
- Biosimilar granulocyte–colony-stimulating factor for healthy donor stem cell mobilization: need we be afraid?
- Unchanged global fibrinolytic capacity during the course of hematopoietic stem cell transplantation
- Innate immunity: a key player in the mobilization of hematopoietic stem/progenitor cells
- Autologous bone marrow stem cell mobilization induced by granulocyte colony-stimulating factor after myocardial infarction
- Thrombotic and hemorrhagic complications in children and young adult recipients of Hematopoietic Stem Cell Transplant (HSCT).
- Hepatic sinusoidal obstruction syndrome secondary to intravesical instillation of mitomycin-C
- Mapping the Structural and Dynamic Determinants of pH-sensitive Heparin Binding to Granulocyte Macrophage-colony Stimulating Factor
- Mapping the Structural and Dynamic Determinants of pH-sensitive Heparin Binding to Granulocyte Macrophage-colony Stimulating Factor.
- The SARS-CoV-2/Receptor Axis in Heart and Blood Vessels: A Crisp Update on COVID-19 Disease with Cardiovascular Complications
- Drugs acting on the immune system
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