Influence of 5'-terminal m7G and 2'--O-methylated residues on messenger ribonucleic acid binding to ribosomes.
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Summary
Evidence is presented to show that the 2'-O-methylated nucleoside of the 5'-terminal cap has a positive influence on the ribosome binding of viral mRNA and of capped synthetic ribopolymers.
- Type
- article
- Published
- 1976-12-28
- Cited by
- 92
- References
- 29
- OpenAlex
- https://openalex.org/W2019784454
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26650153
Keywords
Ribosome, Chemistry, Terminal (telecommunication), Messenger RNA, RNA
References
- Translation in vitro of vesicular stomatitis virus mRNA lacking 5′-terminal 7-methylguanosine
- The 5' terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus.
- Ribosome binding to reovirus mRNA in protein synthesis requires 5' terminal 7-methylguanosine.
- The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.
- Methylation-dependent translation of viral messenger RNAs in vitro.
- Synthesis of pppGpN type dinucleotide derivatives: the 5' end sequence of some RNAs.
- Translational discrimination of ‘capped’ and ‘non‐capped’ mRNAS: inhibition by a series of chemical analogs of m7 GpppX
- Methylated and blocked 5' termini in vesicular stomatitis virus in vivo mRNAs.
- Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.
- In vivo methylation of vesicular stomatitis virus and its host-cell messenger RNA species.
- Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit.
- Rigid structural requirement of the 5' terminus of mRNA for translational activity.
- Novel initiation of RNA synthesis in vitro by vesicular stomatitis virus
- 5'-terminal structure of poliovirus polyribosomal RNA is pUp.
- A protein binding the methylated 5'-terminal sequence, m7GpppN, of eukaryotic messenger RNA.
- 5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation
- Inhibition of initiation of protein synthesis by 7-methylguanosine-5'-monophosphate.
- Inhibition of the transition of a 40S ribosome–Met-tRNAiMet complex to an 80S ribosome–Met-tRNAiMet complex by 7-methylguanosine-5′-phosphate
- Bacteriophage T3 and T7 early RNAs are translated by eukaryotic 80S ribosomes: active phage T3 coded S-adenosylmethionine cleaving enzyme is synthesized.
- Effect of 5'-terminal structure and base composition on polyribonucleotide binding to ribosomes.
Cited by
- Cleavage of pm7G from mRNA 5′terminal cap structures by pyrophosphatase activity in embryonic chick lens cells
- Functions of the 5′‐terminal m7G cap in eukaryotic mRNA
- Priming of influenza viral RNA transcription by capped heterologous RNAs.
- Viruses as probes for development and differentiation.
- Probing the function of the eukaryotic 5'-cap structure using monoclonal antibodies to cap-binding proteins.
- Structural biology of eIF4F: mRNA recognition and preparation in eukaryotic translation initiation.
- Translation of plant virus messenger RNAs.
- Mechanism of mRNA recognition by eukaryotic ribosomes during initiation of protein synthesis.
- General RNA binding proteins render translation cap dependent.
- Biosynthesis of reovirus-specified polypeptides. Initiation of reovirus messenger RNA translation in vitro and identification of methionyl-x initiation peptides.
- Influence of 5' proximal secondary structure on the translational efficiency of eukaryotic mRNAs and on their interaction with initiation factors.
- The functional significance of leader and trailer sequences in eukaryotic mRNAs.
- Translation of brain messenger ribonucleic acids in homologous, heterologous and mixed cell free systems.
- 5'-Terminal 7-methylguanosine and mRNA function. The effect of enzymatic decapping and of cap analogs on translation of tobacco-mosaic-virus RNA and globin mRNA in vitro.
- Different cap 1 : cap 2 ratios in rabbit α and β globin mRNA
- Translation of vitellogenin mRNA in the presence of 7-methylguanosine 5'-triphosphate. Cap analogs compete with mRNAs on the basis of affinity for initiation-complex formation.
- The effect of "cap" analogs on reovirus mRNA binding to wheat germ ribosomes. Evidence for enhancement of ribosomal binding via a preferred cap conformation.
- Biosynthesis of reovirus-specified polypeptides. System-dependent effect of reovirus mRNA methylation on translation in vitro catalyzed by ascites tumor and wheat embryo cell-free extracts.
- 5'-terminal cap structure in eucaryotic messenger ribonucleic acids.
- Capped mRNAs with Reduced Secondary Structure Can Function in Extracts from Poliovirus-Infected Cells
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