Ordering of C-terminal loop and glutaminase domains of glucosamine-6-phosphate synthase promotes sugar ring opening and formation of the ammonia channel.

Keywords

Glutamine amidotransferase, ATP synthase, Chemistry, Active site, Transferase

References

• Glucosamine metabolism. V. Enzymatic synthesis of glucosamine 6-phosphate.Sudhamoy Ghosh, Harold J. Blumenthal, Eugene A. Davidson — 1960
• From Lobry de Bruyn to enzyme-catalyzed ammonia channelling: molecular studies of D-glucosamine-6P synthase.A. Teplyakov, Caroline Leriche, G. Obmolova — 2002
• Glucosamine-6-phosphate synthase from Escherichia coli: mechanism of the reaction at the fructose 6-phosphate binding siteBéatrice Golinelli‐Pimpaneau, François Le Goffic, Bernard Badet — 1989
• Channeling of ammonia in glucosamine-6-phosphate synthase.A. Teplyakov, G. Obmolova, Bernard Badet — 2001
• Possible involvement of Lys603 from Escherichia coli glucosamine-6-phosphate synthase in the binding of its substrate fructose 6-phosphate.Béatrice Golinelli‐Pimpaneau, Bernard Badet — 1991
• The CCP4 suite: programs for protein crystallography.Number Collaborative Computational Project — 1994
• Refinement of macromolecular structures by the maximum-likelihood method.Garib N. Murshudov, A. A. Vagin, E. J. Dodson — 1997
• Glucosamine synthetase from Escherichia coli: kinetic mechanism and inhibition by N3-fumaroyl-L-2,3-diaminopropionic derivatives.Bernard Badet, Patricia Vermoote, François Le Goffic — 1988
• Conformational changes in ammonia-channeling glutamine amidotransferases.Stéphane Mouilleron, Béatrice Golinelli‐Pimpaneau — 2007
• Glutamine Binding Opens the Ammonia Channel and Activates Glucosamine-6P Synthase*Stéphane Mouilleron, Marie‐Ange Badet‐Denisot, Béatrice Golinelli‐Pimpaneau — 2006
• Structural insights into the mechanism of the PLP synthase holoenzyme from Thermotoga maritima.Fairuz Zein, Yan Zhang, You-Na Kang — 2006
• The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, l-tryptophanGlen Spraggon, Choel Kim, Nguyen‐Huu Xuong — 2001
• The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans.J.E. Raczynska, Jarosław Olchowy, Peter V. Konariev — 2007
• The mechanism of sugar phosphate isomerization by glucosamine 6‐phosphate synthaseA. Teplyakov, G. Obmolova, Marie‐Ange Badet‐Denisot — 2008
• Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site.Joseph M. Krahn, Jeong Hyun Kim, Mark R. Burns — 1997
• Involvement of the C terminus in intramolecular nitrogen channeling in glucosamine 6-phosphate synthase: evidence from a 1.6 A crystal structure of the isomerase domain.A. Teplyakov, G. Obmolova, Marie‐Ange Badet‐Denisot — 1998
• Ammonia channeling in bacterial glucosamine‐6‐phosphate synthase (Glms): Molecular dynamics simulations and kinetic studies of protein mutantsNicolas Floquet, Stéphane Mouilleron, Rasha Daher — 2007
• On the contributions of the internal modes of molecules to the Debye–Waller factorsC. Scheringer — 1972
• Use of TLS parameters to model anisotropic displacements in macromolecular refinement.Martyn Winn, Michail N. Isupov, Garib N. Murshudov — 2001
• Domain motions of glucosamine‐6P synthase: Comparison of the anisotropic displacements in the crystals and the catalytic hinge‐bending rotationStéphane Mouilleron, Béatrice Golinelli‐Pimpaneau — 2007

Cited by

• Anti-uropathogenic activity, drug likeness, physicochemical and molecular docking assessment of (E-)-N′-(substituted-benzylidene)-2-(quinolin-8-yloxy) acetohydrazideEssa Ajmi Alodeani, Mohammad Arshad, Mohammad Asrar Izhari — 2015
• Inactivation of Glucosamine‐6‐Phosphate Synthase by N3‐Oxoacyl Derivatives of L‐2,3‐Diaminopropanoic AcidR. Jedrzejczak, Marek Wojciechowski, Ryszard Andruszkiewicz — 2012
• A molecular pathway for the egress of ammonia produced by nitrogenaseIan Dance — 2013
• Collective motions in glucosamine-6-phosphate synthase: influence of ligand binding and role in ammonia channelling and opening of the fructose-6-phosphate binding site.Nicolas Floquet, Philippe Durand, Bernard Maigret — 2009
• Peptidoglycan biosynthesis machinery: A rich source of drug targetsAnkur Gautam, Rajan Vyas, Rupinder Tewari — 2011
• Utilization of protein intrinsic disorder knowledge in structural proteomicsChristopher J. Oldfield, Bin Xue, Ya-Yue J. Van — 2012
• Highlights of glucosamine-6P synthase catalysis.Philippe Durand, Béatrice Golinelli‐Pimpaneau, Stéphane Mouilleron — 2008
• Synthesis, antimicrobial, analgesic activity, and molecular docking studies of novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde derivativesN D Jayanna, H. M. Vagdevi, J. C. Dharshan — 2013
• Molecular docking studies of some new imidazole derivatives for antimicrobial propertiesA.M. Vijesh, Arun M. Isloor, Sandeep Telkar — 2013
• A Conserved Glutamate Controls the Commitment to Acyl-adenylate Formation in Asparagine SynthetaseMegan E. Meyer, Jemy A. Gutierrez, Frank M. Raushel — 2010
• Synthesis and evaluation of an N-acetylglucosamine biosynthesis inhibitor.Juliana L. Sacoman, Rawle I. Hollingsworth — 2011
• Identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: indolenyl sulfonamide derivatives.Zahid H. Chohan, Moulay Hfid Youssoufi, Aliasghar Jarrahpour — 2010
• Dynamics of glucosamine-6-phosphate synthase catalysis.Stéphane Mouilleron, Marie‐Ange Badet‐Denisot, Bernard Badet — 2011
• Monitoring the Dynamics of Monomer Exchange Using Electrospray Mass Spectrometry: The Case of the Dimeric Glucosamine-6-Phosphate SynthaseGuillaume Chevreux, Cédric Atmanène, Philippe Lopez — 2011
• Structural Basis for Morpheein-type Allosteric Regulation of Escherichia coli Glucosamine-6-phosphate SynthaseStéphane Mouilleron, Marie‐Ange Badet‐Denisot, Ludovic Pecqueur — 2012
• Characterization of a UDP-N-acetylglucosamine biosynthetic pathway encoded by the giant DNA virus Mimivirus.Francesco Piacente, Cinzia Bernardi, Margherita Marin — 2014
• A New Isoindoline Based Schiff Base Derivative as Cu(II) Chemosensor: Synthesis, Photophysical, DNA Binding and Molecular Docking StudiesPattan Sirajuddin Nayab, Madhusudana Pulaganti, Suresh Kumar Chitta — 2015
• Synthesis, spectral characterization, structural studies, molecular docking and antimicrobial evaluation of new dioxidouranium(VI) complexes incorporating tetradentate N2O2 Schiff base ligandsS. Yousef Ebrahimipour, Iran Sheikhshoaie, Jesús Castro — 2015
• Antimicrobial activity of aroylhydrazone-based oxido vanadium(v) complexes: in vitro and in silico studiesS. Yousef Ebrahimipour, Iran Sheikhshoaie, Jim Simpson — 2016
• Intrinsically disordered proteins in molecular recognition and structural proteomicsChristopher J. Oldfield — 2014

Related papers

• Phylogenic aspects of different regulatory mechanisms of glutamine metabolism.Nobuhiko Katunuma, Yoshiko Matsuda, Yasuhiro Kuroda — 1970
• Catalysis uncoupling in a glutamine amidotransferase bienzyme by unblocking the glutaminase active site.Felix List, M. Cristina Vega, Adelia Razeto — 2012
• Evidence that class I glutamine amidotransferase, GAT1_2.1, acts as a glutaminase in roots of Arabidopsis thaliana.Shrikaar Kambhampati, Aga Pajak, Frédéric Marsolais — 2021
• Glutamine代謝の同化と異化の相互調節 : Glutamine F-6-P amidotransferaseとGlutaminaseを材料として易穂 西井 — 1968
• Interdomain Signaling in Glutamine Phosphoribosylpyrophosphate Amidotransferase*Aloke Kumar Bera, Sihong Chen, Janet L. Smith — 1999
• Activation of glutaminase by phosphoribosyl-pyrophosphate and its interference with the assay of phosphoribosylpyrophosphate amidotransferase.Rolf Hahn, Walter Oberrauch, Dieter Mecke — 1979
• Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate.Hongmin Li, Thomas J. Ryan, Karen J. Chave — 2002
• Mechanistic studies of reaction coupling in Glu-tRNAGln amidotransferase.Kurumi Y. Horiuchi, Mark R. Harpel, Li Shen — 2001
• Thermodynamic characterization of the protein-protein interaction in the heteromeric Bacillus subtilis pyridoxalphosphate synthase.Martina Neuwirth, Karlheinz Flicker, Marco Strohmeier — 2007
• Glutamine phosphoribosylpyrophosphate amidotransferase.James Β. Wyngaarden — 1972