TRIM24 links a noncanonical histone signature to breast cancer
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Summary
The PHD-Bromo of TRIM24 provides a structural rationale for chromatin activation through a non-canonical histone signature, establishing a new route by which chromatin readers may influence cancer pathogenesis.
- Type
- article
- Published
- 2010-12-16
- Cited by
- 436
- References
- 64
- Access
- Open access
- OpenAlex
- https://openalex.org/W2017297735
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4386859
Keywords
Histone, Chromatin, Bromodomain, Biology, PHD finger
References
- Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
- A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
- A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins
- Physical properties of estrogen receptor complexes in MCF-7 human breast cancer cells. Differences with anti-estrogen and estrogen.
- Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides.
- Multivalent engagement of chromatin modifications by linked binding modules
- Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.
- An Oestrogen Receptor α-bound Human Chromatin Interactome
- Long-range transcriptional control of progesterone receptor gene expression.
- The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.
- Accurate Whole Human Genome Sequencing using Reversible Terminator Chemistry
- p53-Targeted LSD1 Functions in Repression of Chromatin Structure and Transcription In Vivo
- Version 1.2 of the Crystallography and NMR system
- Crystal structure and mechanism of human lysine-specific demethylase-1
- Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
- Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
- Structural basis of preinitiation complex assembly on human Pol II promoters
- How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
- Trim24 targets endogenous p53 for degradation
- Signaling by estrogens
Cited by
- Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation
- Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data
- K-acetylation and its enzymes: overview and new developments.
- Inhibition of retroviral replication by members of the TRIM protein family.
- DISSECTING THE ROLES OF TRIM24 IN REGULATION OF HEPATIC LIPID METABOLISM AND INFLAMMATION
- High throughput strategy to identify inhibitors of histone-binding domains
- Research Methods for Clinical Trials in Personalized Medicine: A Systematic Review
- Regulation of cellular signalling pathways by Adenovirus
- TRIM24-REGULATED ESTROGEN RESPONSE IS DEPENDENT ON SPECIFIC HISTONE MODIFICATIONS IN BREAST CANCER CELLS
- Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF
- Linking cohesin-dependent transcription with cell pluripotency
- 抗 TIF1 抗体陽性皮膚筋炎の3例
- H4K16 acetylation during embryonic stem cell differentiation
- Histone profiles in cancer.
- Mulibrey nanism: Characterization of hypogonadism, infertility and tumors
- Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1
- Phosphatidylinositol-4-phosphate 5-Kinase 1α Modulates Ribosomal RNA Gene Silencing through Its Interaction with Histone H3 Lysine 9 Trimethylation and Heterochromatin Protein HP1-α*
- Unraveling the Glioma Epigenome—From Molecular Mechanisms to Novel Biomarkers and Therapeutic Targets
- A cascade of molecular events during neural induction
- Dissecting the Interaction between p53 and TRIM24
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